您所在的位置: 首页 --> 导师团队 --> 吴楠

导师基本信息

  • 姓名:吴楠
  • 性别:
  • 民族:汉族
  • 科室:胸外科二病区
  • 职称:主任医师,教授
  • 专业:肿瘤学、肿瘤外科学、中西医结合临床
  • E-MAIL: nanwu@bjmu.edu.cn

学术论文 | 出版专著 | 奖励表彰 | 研究方向 | 专利 | 科研项目 | 招生计划

Xuantong Zhou#, Furong Huang#, Gang Ma#, Wenqing Wei, Nan Wu* and Zhihua Liu*. Dysregulated ceramides metabolism by fatty acid 2-hydroxylase exposes a metabolic vulnerability to target cancer metastasis,Signal Transduction and Targeted Therapy,2022 Oct 24;7(1):370

Xiang Li, Shanyuan Zhang, Xiang Luo, Guangming Gao, Xiangfeng Luo, Shansi Wang, Shaolei Li, Dachuan Zhao, Yaqi Wang, Xinrun Cui, Bing Liu, Ye Tao, Bufan Xiao, Lei Tang, Shi Yan, and Nan Wu. Accuracy and efficiency of an artificial intelligence-based pulmonary broncho-vascular three-dimensional reconstruction system supporting thoracic surgery: Retrospective and prospective validation study,eBioMedicine,2023 Jan;87:104422

Liu B, Wang C, Fang Z, Bai J, Qian Y, Ma Y, Ruan X, Yan S, Li S, Wang Y, DongB, YangX, LiM, XiaX, QuH, FangX and Wu N. Single-cell RNA sequencing reveals the cellular and molecular changes that contribute to the progression of lung adenocarcinoma,Frontiers in Cell and Developmental Biology,2022;10:927300

Wang Y#, Yang X#, Liu B, Yan S, Liu M, Li X, Li S, Lv C, Ma Y, Zhou L, Song Z, Xv W, Yang Y, Lin D*, Wu N*. Percentage of Newly Proposed High-Grade Patterns Is Associated with Prognosis of Pathological T1-2N0M0 Lung Adenocarcinoma,Ann Surg Oncol,2022 Feb 24

Hu D#, Li S#, Zhang H, Wu N, Lu X*. Using Natural Language Processing and Machine Learning to Preoperatively Predict Lymph Node Metastasis for Non-Small Cell Lung Cancer With Electronic Medical Records: Development and Validation Study,JMIR Med Inform,2022 Apr 25;10(4):e35475

Hu D, Li S, Wu N, Lu X. A Multi-modal Heterogeneous Graph Forest to Predict Lymph Node Metastasis of Non-small Cell Lung Cancer,IEEE J Biomed Health Inform,2023 Jan 2;PP

Hu D, Zhang H, Li S, Duan H, Wu N, Lu X. An ensemble learning with active sampling to predict the prognosis of postoperative non-small cell lung cancer patients,BMC Med Inform Decis Mak,2022 Sep 19;22(1):245

Hu D, Zhang H, Li S, Wang Y, Wu N, Lu X. Automatic Extraction of Lung Cancer Staging Information From Computed Tomography Reports: Deep Learning Approach,JMIR Med Inform,2021 Jul 21;9(7):e27955

Li J#, Liu B#, Ye Q#, Xiao X, Yan S, Guan W, He L, Wang C, Yu Z, Tai Z, Pei S, Ma Y, Li S, Wang Y, Wu N. Comprehensive genomic analysis of primary malignant melanoma of the esophagus reveals similar genetic patterns compared with epithelium-associated melanomas,Modern Pathology,2022 Jun 10

Xing Wang, Li Zhang et al. Deep learning combined with radiomics may optimize the prediction in T differentiating high-grade lung adenocarcinomas in ground glass opacity lesions on CT scans,European Journal of Radiology,

Shaolei Li, Shi Yan, Fangliang Lu, Chao Lv, Yaqi Wang, Xiang Li, Yuzhao Wang, Yue Yang & Nan Wu. Validation of the 8th Edition Nodal Staging and Proposal of New Nodal Categories for Future Editions of the TNM Classification of Non-Small Cell Lung Cancer.,ANNALS OF SURGICAL ONCOLOGY,

Shen L#, Xiao Y#, Zhang C, Li S, Teng X, Cui L, Liu T, Wu N*, Lu Z*. Metabolic reprogramming by ex vivo glutamine inhibition endows CAR-T cells with less-differentiated phenotype and persistent antitumor activity,Cancer Lett,2022 Jul 10;538:215710

Xiao BF#, Zhang JT#, Zhu YG#, Cui XR, Lu ZM, Yu BT*, Wu N*. Chimeric Antigen Receptor T-Cell Therapy in Lung Cancer: Potential and Challenges,Frontiers In Immunology,2021 Nov 1;12:782775

Juntuo Zhou, Bing Liu, Zhongwu Li3, Yang Li4, Xi Chen4, Yuanyuan Ma1, Shi Yan1, Xin Yang3, Lijun Zhong5,# and Nan Wu. Proteomic analyses identify differentially expressed proteins and pathways between low-risk and high-risk subtypes of early-stage lung adenocarcinoma and their prognostic impacts,Molecular Cellular Proteomics,

Wang Y#, Pei Y#, Lv C, Wang Y, Wang J, Zhao D, Li X, Yang Y, Kim AW, Toker A, Yan S*, Wu N*. Intermittent chest tube clamping decreases chest tube duration time and drainage volume after lung cancer surgery in patients without air leak: an open-label, randomized controlled trial,Transl Lung Cancer Res,2022 Mar;11(3):357-365

Dong Z#, Yan S#, Liu B, Hao Y, Lin L, Chang T, Sun H, Wang Y, Li H, Wu H, Hang X, He S, Hu J, Xue X*, Wu N*, Chang L*. Single Living Cell Analysis Nanoplatform for High-Throughput Interrogation of Gene Mutation and Cellular Behavior. Nano Lett.,Nano letters,2021 Jun 9;21(11):4878-4886

Nan Wu, Sixue Liu, Jingjing Li, Zhenyu Hu, Shi Yan, Hongwei Duan, Dafei Wu, Yuanyuan Ma, Shaolei Li, Xing Wang, Yaqi Wang, Xiang Li, Xuemei Lu. Deep sequencing reveals the genomic characteristics of lung adenocarcinoma presenting as ground-glass nodules (GGNs),Translational Lung Cancer Research,

Xiang Li,Shi Yan,Yuanyuan Ma,Shaolei Li,Yaqi Wang,Xing Wang,Yuzhao Wang,Jia Wang,Chao Lv,Yue Yang,NanWu Impact of Early Oral Feeding on Anastomotic Leakage Rate After Esophagectomy: A Systematic Review and Meta-analysis,World J Surg,

Danqing Hu,Shaolei Li,Zhengxing Huang,Nan Wu,Xudong Lu. Predicting postoperative non-small cell lung cancer prognosis via long short-term relational regularization,Artificial Intelligence in Medicine,Volume 107

Jia Wang, Nan Wu, Chao Lv, Shi Yan, Yue Yang. Recommended changes for the 8th edition of the TNM classification for lung cancer-the findings of a single-institution evaluation,Annals of Translational Medicine,

Si J, Ma Y, Bi JW, Xiong Y, Lv C, Li S, Wu N, Yang Y. Shisa3 brakes resistance to EGFR-TKIs in lung adenocarcinoma by suppressing cancer stem cell properties. J Exp Clin Cancer Res.,Journal of Experimental and Clinical Cancer Research,2019 Dec 4;38(1):481

Xiang Li, Shi Yan, Jichun Yang, Yaqi Wang, Chao Lv, Shaolei Li, Jun Zhao, Yue Yang, Minglei Zhuo and Nan Wu . Efficacy and Safety of PD-1/PD-L1 Inhibitors Plus Chemotherapy Versus PD-1/PD-L1 Inhibitors in Advanced Non-Small Cell Lung Cancer: A Network Analysis of Randomized Controlled Trials,Frontiers in Oncology,

Liu B#, Wang Y#, Wang H, Li Z, Yang L, Yan S, Yang X, Ma Y, Gao X, Guan Y, Yi X, Xia X*, Li J*, Wu N*. RBM10 Deficiency Is Associated With Increased Immune Activity in Lung Adenocarcinoma,Frontiers in Oncology,2021 Jul 21;11:677826

Jiahui Si, Yuanyuan Ma, Ji Wang Bi, Ying Xiong, Chao Lv, Shaolei Li, Nan Wu & Yue Yang Shisa3BrakesResistancetoEGFR-TKIsinLungAdenocarcinomabySuppressingCancerStemCellProperties,J Exp Clin Cancer Res,38: 481

Zhang H#, Hu D#, Duan H, Li S, Wu N*, Lu X*. A novel deep learning approach to extract Chinese clinical entities for lung cancer screening and staging,BMC Medical Informatics and Decision Making,2021 Jul 30;21(Suppl 2):214

Jun Ni#, Miao Huang#, Li Zhang*, Nan Wu* et al.Clinical recommendations for perioperative immunotherapy- induced adverse events in patients with non-small cell lung cancer,Thoracic Cancer,2021 May;12(9):1469-1488

倪军#, 黄淼#, 张力*, 吴楠*等. 非小细胞肺癌围手术期免疫治疗相关不良反应管理的临床诊疗建议,中国肺癌杂志,2021,24(3):141-160

赵大川, 阎石, 王亚旗, 马媛媛, 王兴, 李少雷, 李想, 吕超, 王宇昭, 王嘉, 杨跃, 吴楠. N1 期非小细胞肺癌患者肺内转移淋巴结解剖部位与疾病复发风险及预后的关系分析,中华医学杂志,2021, 101(35): 2778-2786

阎石,吴楠. 基于非小细胞肺癌系统性肺内淋巴结清扫的N1分期改良建议,中华医学杂志,2021,101(35):2748-2750

郏博, 吕超, 常建华, 吴楠*, 王子平*等. 非小细胞肺癌非常见突变靶向治疗研究进展,中华医学杂志,2022, 102(13) : 969-976

《老年肺癌综合治疗学》, 主编, 北京大学医学出版社, 2020.11

《肺癌规范化手术》, 主编, 北京大学医学出版社, 2022.12

《非小细胞肺癌非常见基因突变诊治策略》, 主编, 北京大学医学出版社, 2021.12

《食管癌规范化手术》, 参编, 北京大学医学出版社, 2023.3

登峰人才计划, 登峰人才计划, 第1完成人, 北京市医院管理局, 2019.11

一种锁骨下静脉穿刺置管穿刺点选择辅助装置, 实用新型, 第1完成人, 国家专利局, 中国, 2022.3

一种胸腔镜镜头防雾装置, 实用新型, 第1完成人, 国家专利局, 中国, 2023.6

silncRNA16 及其治疗铂类耐药肿瘤中的用途, 发明专利, 第2完成人, 国家专利局, 中国, 2023.6

基于血浆 cfDNA 多组学检测的肺癌早筛及结节风险度评模型构建, 课题负责人, 2022.12.16~2025.12.31, 北京市自然科学基金

TumorX共建联合实验室, 课题负责人, 2022.7.1~2032.7.31, 无锡臻和生物科技有限公司

肺癌临床研究标准数据集, 课题负责人, 2022.11.1~2023.11.30, 北京市卫生和计划生育委员会适宜技术推广项目

登峰人才计划:胸外科学及肿瘤学(吴楠), 课题负责人, 2020.1.1~2023.12.31, 北京市医管中心登峰

LncRNA16抑制细胞焦亡信号通路参与非小细胞肺癌耐药机制和应用的研究, 课题负责人, 2020.6.1~2023.12.29, 国家自然科学基金面上项目

Durvalumab 联合顺铂+白蛋白结合型紫杉醇作为术前新辅助疗法用于可切除食管鳞癌的前瞻、单臂临床试验, 课题负责人, 2021.4.1~2024.3.31, CSCO

老年肺癌手术风险预测模型的构建及临床应用研究, 课题负责人, 2020.6.1~2023.5.31, 首都卫生发展科研专项

肿瘤的多学科协作临床决策支持系统研发与实践, 课题负责人, 2018.7.15~2020.12.15, 国家重点研发计划“精准医学研究”重点专项

基于标准化手术和大数据分析模拟非小细胞肺癌淋巴结转移模式的算法研究及临床应用研究, 课题负责人, 2018.1.15~2020.12.15, 北京市医管局 “扬帆计划”

NFATc2调控非小细胞肺癌肿瘤起始细胞-巨噬细胞免疫逃逸的分子机制及治疗策略, 课题负责人, 2019.1.7~2021.12.7, 北京市自然科学基金/7192036

非小细胞肺癌转移淋巴结浸润免疫细胞异质性的研究, 课题负责人, 2019.1.15~2020.12.15, 北京市人力资源和社会保障局

肺癌常规手术治疗基础上补充进行肺内淋巴结分检的临床应用及预后意义研究, 课题负责人, 2016.6.1~2019.6.30, 北京市科技计划课题(首都特色项目)/Z161100000516063

研究生招生计划
招生年度 招生专业 学位级别 学位类型 研究方向 选拔方式 操作
2024 肿瘤学 博士 科学学位 (医学创新交叉项目)肿瘤免疫微环境 申请考核制

社会任职

  • 欧洲肺癌大会(ELCC) 学术委员会委员
  • 中国临床肿瘤学会智慧医疗专家委员会 副主任委员
  • 国际肺癌研究协会(IASLC)会员委员会主席
  • 中华医学会肿瘤学分会 委员
  • 中国医师协会肿瘤多学科诊疗专业委员会 常务委员

学习、工作经历

  • 2022.6.1~,北京大学肿瘤医院副院长
  • 2018.3.11~2019.9.11,中组部第八批援藏干部,在西藏大学医院院任常务副院长、院长
  • 2016.8.1~,北京大学肿瘤医院胸部肿瘤中心副主任
  • 2004.4.12~,北京大学肿瘤医院胸外科
  • 2001.8.30~2003.8.12,美国新泽西州州立大学博士后