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导师基本信息

  • 姓名:郝纯毅
  • 科室:肝胆胰外科-II
  • 职称:主任医师
  • 专业:肿瘤学
  • E-MAIL: haochunyi@gmail.com

研究方向

软组织与腹膜后肿瘤的综合治疗

肝胆胰腺肿瘤的诊断和治疗

转移性大肠癌的诊断与治疗

发表学术论文| 出版的专著| 获得的成果、奖励

Zhang Yi, Guan Xiao-Ya, Dong Bin, Zhao Min, Wu Jian-Hui, Tian Xiu-Yun*, Hao Chun-Yi*.Expression of MMP-9 and WAVE3 in colorectal cancer and its relationship with clinicopathologic features

Xiao-Sun Yuan, Yi Zhang, Xiao-Ya Guan, Bin Dong, Min Zhao, Lin-lin Mao, Xiu-Yun Tian*, Chun-Yi Hao*.p42.3: A promising biomarker for the progression and prognosis of human colorectal cancer

Ang Lv#, Zhong-Wu Li#, Xiu-Yun Tian, Xiao-Ya Guan, Min Zhao, Bin Dong, Chun-Yi Hao*.SKP2 high expression, KIT exon 11 deletions, and gastrointestinal bleeding as predictors of poor prognosis in primary gastrointestinal stromal tumors

Yi Zhang#, Xiu-Yun Tian#, Hong Ji, Xiao-Ya Guan, Bin Dong, Min Zhao, Meng Wei, Chun-Xiang Ye, Yuan Sun, Xiao-Sun Yuan, Chen Yang, Wen-Mei Li, Jian-Tao Cui, Chun-Yi Hao*. Expression of SATB1 Promotes the Growth and Metastasis of Colorectal Cancer.

Qian Honggang#, Wei Meng#, Qiu Hui, Wu Jianhui, Liu Bonan, Lyu Ang, Liu Qiao, Li Chengpeng, Leng Jiahua,Zhang Ji and Chun-Yi Hao*.A scoring system for prediction of early recurrence after liver resectionfor Barcelona Clinic Liver Cancer stage B hepatocellular carcinoma

Xiu-Yun Tian#, Chun-Xiang Ye#, Yong-Yong Yang, Xiao-Ya Guan, Bin Dong, Min Zhao, Chun-Yi Hao*. Expression of CD147 and matrix metalloproteinase‑11 in colorectal cancer and their relationship to clinicopathological features.

Ang Lv, Wendy Liu, Hong-gang Qian, Jia-hua Leng and Chun-Yi Hao*.Reactive lymphoid hyperplasia of the liver mimicking hepatocellular carcinoma: incidental finding of two cases.

Shaoping Ling#, Zheng Hu#, Zuyu Yang#, Fang Yang, Yawei Li, Pei Lin, Ke Chen, Lili Dong, Lihua Cao, Yong Tao, Lingtong Hao, Qingjian Chen, Qiang Gong, Dafei Wu, Wenjie Li, Wenming Zhao, Xiuyun Tian, Chunyi Hao*, Eric A. Hungate, Daniel V. T. Catenacci, Richard R. Hudson, Wen-Hsiung Li*, Xuemei Lu*, and Chung-I Wu*(Co-corresponding author). Extremely high genetic diversity in a single tumor points to prevalence of non-Darwinian cell evolution.

Xiu-Yun Tian#, Liang Yan#, Dong-Hai Zhang, Xiao-Ya Guan, Bin Dong, Min Zhao, Chun-Yi Hao*. PTK7 overexpression in colorectal tumors: clinicopathological correlation and prognosis relevance.

Xiao-Jing Cheng#, Xiu-Yun Tian#, Xiao-Jiang Wu#, Xiao-Fang Xing, Hong Du, Chun-Lian Zhou, Qing-Yun Zhang, Chun-Yi Hao*, Xianzi Wen*, Jia-Fu Ji*. Relationship between LAPTM4B gene polymorphism and prognosis of patients following tumor resection for colorectal and esophageal cancers.

Chun-Xiang Ye#, Xiu-Yun Tian#, Guan-Jun Yue, Liang Yan, Xiao-Ya Guan, Shan Wang, Chun-Yi Hao*. Suppression of CD26 inhibits growth and metastasis of pancreatic cancer.

Chun-Xiang Ye#, Xiu-Yun Tian#, Liang Yan, Xiao-Ya Guan, Sheng-Ju Yin, Chun-Yi Hao*. Elevated serum CD26 level is associated with metastasis and post-operation survival in pancreatic cancer patients

Yuan Sun#, Qi-Ming An#, Xiu-Yun Tian#, Zi-Lei Wang, Xiao-Ya Guan, Bin Dong, Min Zhao, Chun-Yi Hao*. Fusobacterium nucleatum infection is correlated with tumor metastasis and postoperative survival of colorectal cancer patients in China.

Dao-Ning Liu, Ang Lv, Zhi-Hua Tian, Xiu-Yun Tian, Xiao-Ya Guan, Bin Dong, Min Zhao, Chun-Yi Hao*. Superior mesenteric artery margin in pancreaticoduodenectomy for pancreatic ademocarcinoma.

Yuan Sun#, Qi-Ming An#, Xiu-Yun Tian#, Zi-Lei Wang, Xiao-Ya Guan, Bin Dong, Min Zhao, Chun-Yi Hao*. Fusobacterium nucleatum infection is correlated with tumor metastasis and postoperative survival of colorectal cancer patients in China.

Xiang-qian Su, Chun-Yi Hao, Fei Gao, Jia-Fu Ji. Metachronous second primary cancers: clinical analyses of 506 cases in a single institution.

Chun-Yi Hao*,Lin Shen, Jin Gu, Bao-Cai Xing, Xiao-Peng Zhang, Ai-Ping Lu, Min-Hua Chen, Ren-Jie Yang, Ping-Ping Li, Jia-Fu Ji. Guidelines for the management of colorectal liver metastases in Peking University School of Oncology.

Meng Wei, Hong-Gang Qian, Hui Qiu, Ying-Jie Li, Guo-Quan Zhou, Ji Zhang, Chun-Yi Hao*. A scoring system to predict ascites after hepatectomy for hepatoellular carcinoma. Chinese Journal of Surgery. 2010; 48(20):1534-1538

Jian-Hui Wu, Xiu-Yun Tian, Chun-Yi Hao*. The significance of a group of molecular markers and clinicopathological factors in identifying colorectal liver metastases.

Hao CY*. Angiogenesis blockade as therapy for hepatocellular carcinoma: Progress andchallenges. J. Gastroenterol. Hepatol.

Zhang Ji, Zhu Xu, Chen Hui, Qian Hong-Gang, Leng Jia-Hua, Qiu Hui, Wu Jian-Hui, Liu Bo-Nan, Liu Qiao, Lv Ang, Li Ying-Jie, Zhou Guo-Quan, Chun-Yi Hao*

Chun-Yi Hao, Ai-Ping Lu, Bao-Cai Xing, et al. Altered gene expression in normal colonic mucosa of individuals with polyps of the colon.

Stomach-Interposed Cholecystogastrojejunostomy: a Palliative Approach for Periampullary Malignancies

Chen Minhua, Chun-Yi Hao, Zhanghui, et al. Analgesic effect of neurolytic celiac plexus block guided by ultrasonograpy in advanced malignancies.

Chun-Yi Hao, Ai-Ping Lu, Bao-Cai Xing, et al. Alteration of gene expression in macroscopically normal colonic mucosa from individuals with a family history of sporadic colon cancer.

Kang B, Hao C#, Wang H, et al.Evaluation of hepatic-metastasis risk of colorectal cancer upon the protein signature of PI3K/AKT pathway

Ji Zhang, Hong-Gang Qian, Chun-Yi Hao*. Long mesentericoportal vein resection and end-to-end anastomosis without graft in pancreaticoduodenectomy

Chun-Yi Hao, Huang Xinfu: Progress in the study of Multidrug Resistance (Review). Chinese Journal of Clinical Oncology. 1994,21(11): 855-60

Chun-Yi Hao, He Luowen: Progress in study of oncogene and tumor suppresser gene in breast cancer(Review). Medicine Abroad. 1995,12(3):@4-30

Wang Hongyi, Chun-Yi Hao, et al: Expression of Epidermal Growth Factor Receptor in breast cancer-Its Prognostic Significance and relation with Steroid hormone Receptors. Chinese Journal of Clinical Oncologfy.1995,22(4):229-32

Chun-Yi Hao,Xing Baocai, Huang Xinfu: A case report: A misdiagnoses in a pregnancy woman with ovary cancer. Chinese Journal of Clinical Oncology.1995,22(9):165

He Luowen, Chun-Yi Hao, et al: P-glycoprotein expression in primary breast cancer. Chinese Medical Science Journal. 1995,10(1): 12-15

Tangpeng, Chun-Yi Hao, et al: Prognostic significance of c-erb B-2 protooncogene expression in breast cancer. Chinese Journal of Clinical Oncology. 1995,22(11):780-82

Chun-Yi Hao, Huang Xinfu: Progress in multimodality treatment of gastric cancer (Review). Chinese Journal of General Surgery. 1996,11(5):268-71

Wen Hongwu, Liushuwen, Chun-Yi Hao: Expression and significance of HER-2/neu oncogen in ovary cancer. Journal of Beijing Medical University. 1996,28(3):179

Chun-Yi Hao, Lu Guizhi, et al: Effect of ATP on malignant phenotype of a human gastric cancer cell line. Chinese Journal of Oncology.1999, 21(3):165-7

Chun-Yi Hao, Wangyi, Huang Xinfu: Clinical Analysis of Multiple Primary Cancers. Chinese Journal of Clinical Oncology.1999,26(7):507-10

Wang Tianfeng, Chun-Yi Hao, Ouyang Tao, et al. Comparison of three chemotherapeutic protocols for preoperative breast cancer patients. Chinese Journal of Clinical Oncology. 2000, 27(1):65-66

Chun-Yi Hao, Zhaomin, Liyong, et al. A technique to decrease the false positive rate of differential display PCR .Chinese Journal of Biochemistry and Molecular Biology. 2002, 18(1): 110-114

Zhuqiang, Shanjun, Chun-Yi Hao, et al. Application of spiral CT cholangiography in obstructive jaundice. Chinese Journal of Oncology. 2003, 25(3): 268-271

Chun-Yi Hao, Zhaomin, Liyong, et al. A preliminary study on the isolation of human hepatocellular carcinoma associated genes by mRNA differential display PCR. Chinese Journal of Medical Research an Application. 2004, 5-8

Ling-Chun Chen, Chun-Yi Hao, et al. Alteration of gene expression in normal appearing colon mucosa of APCmin mice and human cancer patients. Cancer Research.2004, May, 64(10): 3694-700

降低mRNA差异显示技术假阳性率的一种方法

Chun-Yi Hao, Jia-Fu Ji. Surgical Treatment of Liver Metastases of Colorectal Cancer: Strategies and Controversies in 2006

Chun-Yi Hao, Ai-Ping Lu, Bao-Cai Xing, et al. Solid Pseudopapillary Tumor of the Pancreas: Report of Eight Cases in a Single Institution and a Review of the Chinese Literature

郝纯毅,赵敏,李勇等,应用mRNA差异显示技术进行肝癌相关基因的筛选

超声引导腹腔神经丛阻滞对上腹部恶性肿瘤的止痛效果

胰腺实性假乳头状肿瘤:临床病理学特征及国人病例报告分析

社会任职

  • IASGO副秘书长,中国抗癌协会胰腺癌专业委员会主任委员
  • 国际外科和胃肠专家学会(IASG)委员、国际肿瘤外科学会(ISSO)委员、《世界华人消化杂志》编委、《Hepatogastroenterology》杂志编委、中华医学会北京肿瘤专业委员会委员、中国老年学学会老年肿瘤专业委员会执行委员会委员。

学习、工作经历

  • 2008.8~2008.9,美国约翰霍普金斯 访问学者
  • 2005.9~2006.2,法国路易巴斯德大学Hopital de Hautepierre肝胆外科中心客座教授
  • 2001.6~2003.8,美国加州太平洋医学中心博士后