您所在的位置: 首页 --> 导师团队 --> 杨志

导师基本信息

  • 姓名:杨志
  • 性别:
  • 民族:汉族
  • 科室:核医学科
  • 职称:研究员
  • 专业:影像医学与核医学
  • E-MAIL: pekyz@13.com

学术论文 | 出版专著 | 奖励表彰 | 专利 | 科研项目 | 招生计划

Xiao Jin#, Maomao Wei#, Shuailiang Wang#, Guochang Wang#, Yumei Lai, Yunfei Shi, Yan Zhang, Zhi Yang, Xuejuan Wang*. Detecting fibroblast activation proteins in lymphoma using 68Ga-FAPI PET/CT,Journal of Nuclear Medicine,2021,DOI: 10.2967/jnumed.121.262134.

Li Hui,Liu Yanqing,Zang Jie et al. Inferior Vena Cava Tumor Thrombus From Thyroid Cancer Detected by 68Ga-PSMA-617 PET/CT.,Clin Nucl Med.,2021, 46: 264-265.

Li Hui, Meng Xiangxi, Guan Xiangping, Zhou Nina, Liu Hui, Zhang Yan, Yu Boqi, Zhu Hua, Li Nan, Yang Zhi*. Clinical Evaluation of MR-Gated RespiratoryMotion Correction in Simultaneous PET/MRI.,Clin Nucl Med.,2021; 46: 297-302.

Shujing Wang#, Hua Zhu#*, Jin Ding, Feng Wang, Lixin Ding, Yan Zhang, Nan Li, Sheng Yao, Xinan Sheng*, Zhi Yang*. Positron Emission Tomography Imaging of Programmed Death 1 Expression in Cancer Patients Using Iodine-124 Labeled Toripalimab: A Pilot Clinical Translation Study.,Clinical Nuclear Medicine,,2021, 46(5),382-388.

Xiaoxia Xu, Hua Zhu, Hank F. Kung, Nan Li*, Zhi Yang*.Benign Adrenal Nodule Mimicking Lymphoma were Differentially Diagnosed by 18F-FDG and 18F-FGln PET/CT.,Clinical Nuclear Medicine,,2021;46:474-476

Zhu Li#, Ziren Kong#, Junyi Chen#, Jiyuan Li, Nan Li, Zhi Yang*, Yu Wang*, Zhibo Liu*. 18F-Boramino acid PET/CT in healthy volunteers and glioma patients.,European Journal of Nuclear Medicine and Molecular Imaging,2021, DOI:10.1007/s00259-021-05212-7.

Jinquan Jiang, Dan Li, Teli Liu, Lei Xia, Xiaoyi Guo, Xiangxi Meng, Feng Wang, Zhi Yang, Hua Zhu*. Noninvasive evaluation of PD-L1 expression using Copper 64 labeled peptide by Micro-PET imaging.,Bioorganic & Medicinal Chemistry Letters.,2021, 40,127901.

Shuailiang Wang#, Xin Zhou#, Xiaoxia Xu#, Jin Ding, Teli Liu, Jinquan Jiang, Nan Li*, Hua Zhu*, Zhi Yang*. Dynamic PET/CT imaging of 68Ga-FAPI-04 in Chinese subjects,Frontiers in Oncology,,2021, 11, 651005.

Qing Xie, Teli Liu, Jing Ding, Nina Zhou, Xiangxi Meng, Hua Zhu, Nan Li, Jiangyuan Yu*, Zhi Yang*.Synthesis, preclinical evaluation, and a pilot clinical imaging study of [18F]AlF-NOTA-JR11 for neuroendocrine neoplasms compared with [68Ga]Ga-DOTA-TATE.,European Journal of Nuclear Medicine and Molecular Imaging,2021, DOI: 10.1007/s00259-021-05249-8.

Lei Xia, Xiangxi Meng, Li Wen, Nina Zhou, Teli Liu, Xiaoxia Xu, Feng Wang, Zhen Cheng, Zhi Yang*, Hua Zhu*. A Highly Specific Multiple Enhancement Theranostic Nanoprobe for PET/MRI/PAI Image-Guided Radioisotope Combined Photothermal Therapy in Prostate Cancer.,Small,2021, DOI: 10.1002/smll.202100378.

Liu Teli#, Liu Chen#, Zhang Zhongyi#, Zhang Ning, Guo Xiaoyi, Xia Lei, Jiang Jinquan, Xie Qing, Yan K, Rowe SP, Zhu Hua, Yang Zhi. 64Cu-PSMA-BCH: a new radiotracer for delayed PET imaging of prostate cancer. Eur J Nucl Med Mol Imaging.,Eur J Nucl Med Mol Imaging,2021 Jun 25. doi: 10.1007/s00259-021-05426-9. Epub ahead of print. PMID: 34170361

Zhu Hua*#; Zhang Hanwen#; Zhou Nina#; Ding Jin; Jiang Jinquan; Liu Teli; Liu Ziyu; Wang Feng; Zhang Qian; Zhang Zhuochen; Yan Shi; Li Lei; Benabdallah Nadia; Jin Hongjun; Liu Zhaofei; Cai Lisheng; Thorek Daniel L. J*.; Yang Xing*; Yang Zhi*。 Molecular PET/CT Profiling of ACE2 Expression In Vivo: Implications for Infection and Outcome from SARS-CoV-2. Adv Sci (Weinh).,ADVANCED SCIENCE,2021 Jun 26:e2100965. doi: 10.1002/advs.202100965. Epub ahead of print. PMID: 34174177. (SCI IF 16.806 Q1 )

Gao Yujie, Yang Zhi, Yu Jiangyuan, Li Nan, Wang Xuejuan, Zhou Nina. Potential application value of PET/computed tomography in retroperitoneal leiomyosarcoma and a literature review.,Nucl Med Commun.,2021 Jul 1;42(7):800-810.

蒋金泉, 李丹, 刘特立, 徐晓霞, 夏雷, 郭晓轶, 朱华*, 杨志. 肿瘤免疫治疗PD-L1靶向新型PET分子探针68Ga-WL12研制、质控及初步生物学研究。,中国医学影像技术.,2021, 37(1), 79-83.

周欣, 张慧媛, 王淑静, 朱华, 杨志, 李囡*. 非小细胞肺癌靶向PET显像的临床研究进展.,[J]中华临床医师杂志(电子版),2021;15(02):123-128.

高玉杰,周妮娜*,李囡,范洋,杨志.~(11)C-MET PET/CT诊断脑胶质瘤术后复发残留的初步研究,实用肿瘤杂志,2021,36(02):154-159.

王帅亮,朱华,杨志*。T细胞核医学分子成像策略在CAR-T免疫治疗中的应用.,中华核医学与分子影像杂志.,2021, 41(3)175-179.

杨敏福,范岩,李文婵,牛娜,孙晓昕,张卫方,张晓丽,王茜,杨志.核素心肌灌注显像报告书写规范,中国医学影像学杂志,2021,29(03):193-195.

李詝,李囡,刘志博,杨志.~(18)F-硼氨酸细胞摄取机制研究,首都医科大学学报,2021,42(01):15-20.

王茜,李囡,霍力,杨吉刚,艾林,李河北,富丽萍,张建华,杨志.核医学~(18)F-FDG PET/CT报告书写规范,[J].中国医学影像学杂志,,2021,29(01):1-3.

李囡,王茜,付占立,景红丽,郑容,于江媛,杨芳,李艳,童冠圣,杨志.核医学单光子显像报告书写规范,中国医学影像学杂志,,2021,29(02):97-99.

王帅亮,朱华,杨志*。T细胞核医学分子成像策略在CAR-T免疫治疗中的应用.,中华核医学与分子影像杂志.,2021, 41(3)175-179.

谢卿,李慧,刘特立,翟士桢,王风,王丽,杨建华(译),朱华,杨志(审校)。美国、欧洲联盟和加拿大能否在放射性药物的临床首次应用规范方面达成共识?,中华核医学与分子影像杂志.,2021, 41(3)185-192

Teli Liu#, Chen Liu#, Yanan Ren, Xiaoyi Guo, Jinquan Jiang, Qing Xie, Lei Xia, Feng Wang, Hua Zhu*, Zhi Yang*. Development of an albumin-based PSMA probe with prolonged half-life.,Frontiers in Molecular Biosciences.,2020, 7. 585024. (SCI IF 5.246Q2 ) PMID: 33392253 PMCID: PMC7773938 DOI: 10.3389/fmolb.2020.585024

王风, 朱华, 李立强, 郭晓轶, 刘特立,杨志*. 新型固体靶核素~(89)Zr的制备、标记和临床前应用研究进展,同位素,2020, 33(02): 117-123.

北京市核医学质量控制和改进中心北京市医师协会核医学医师专科分会. 新冠肺炎非定点救治医院核医学影像检查中的防控措施,中华放射医学与防护杂志,2020, 40(3): 168-172.

Wang Guochang#., Jin Xiao#., Zhu Hua., Wang Shuailiang., Ding Jin., Zhang Yan., Yang Zhi*.,Wang Xuejuan*. (68)Ga-NOTA-FAPI-04 PET/CT in a patient with primary gastric diffuse large B cell lymphoma: comparisons with [(18)F] FDG PET/CT,Eur J Nucl Med Mol Imaging,2020.

Zhou Nina#, Liu Chang#, Guo Xiaoyi#, Xu Yuping, Gong Jifang, Qi Changsong, Zhang Xiaotian, Yang Min*, Zhu Hua*, Shen Lin*,Yang Zhi*. Impact of (68)Ga-NOTA-MAL-MZHER2 PET imaging in advanced gastric cancer patients and therapeutic response monitoring,Eur J Nucl Med Mol Imaging,2020, Jun(20).

陈曙光, 胡鹏程, 樊卫, 莫逸, 王峰, 卢洁, 高永举, 杨志, 赵军, 杜雪梅, 张政,石洪成*. PET/MR全身显像工作流及协议规划专家共识,中国临床医学,2020, 27(04): 713-721.

Xiaojiang Duan#, Futao Liu#, Hongmok Kwon, Youngjoo Byun, Il Minn, Xuekang Cai, Jingming Zhang, Martin G. Pomper, Zhi Yang*, Zhen Xi*, Xing Yang*. (S)-3-(Carboxyformamido)-2-(3-(carboxymethyl)ureido)propanoic Acid as a Novel PSMA Targeting Scaffold for Prostate Cancer Imaging.,Journal of Medicinal Chemistry,.,2020, 63(7):3563-3576

邓虞娇,朱华,杨志,彭志平,贾建华.中枢神经系统临床用PET显像剂的研究进展262.,同位素,2020,33(04):250-262.

Xiaoyi Guo#, Nina Zhou#, Zuhua Chen#, Teli Liu, Xiaoxia Xu, Xia Lei, Lin Shen, Jing Gao, Zhi Yang*, Hua Zhu1,*. Construction of 124I-trastuzumab for Noninvasive PET Imaging of HER2 Expression: From Patient-derived Xenograft Models to Gastric Cancer Patients.,Gastric Cancer. 2020.,2020: 1-13.

Haifeng Huang#, Hua Zhu#, Quan Xie, Xiao-Bin Tian, Xian-Teng Yang, Fan Feng, Qi-Yu Jiang, Xi-Nan Sheng?, Zhi Yang*. Evaluation of 124I-JS001 for hPD1 immuno-PET imaging using sarcoma cell homografts in humanized mice.,Acta Pharmaceutica Sinica B.,2020,

Nina Zhou#, Xiaoyi Guo#, Min Yang, Hua Zhu*, Zhi Yang*.68Ga-ZHER2 PET/CT Reveals HER2-positive Metastatic Gastric Cancer with Better Image Quality than 18F-FDG.,Clinical Nuclear Medicine,,2020, 45(2): e101-e102.

孟天宇, 于江媛, 李囡,杨志*. PET/CT显像在化疗相关心肌损伤中的应用,中华核医学与分子影像杂志,2020, 40(03): 179-182.

Teli Liu?, Chen Liu?, Yanan Ren, Xiaoyi Guo, Jinquan Jiang, Qing Xie, Lei Xia, Feng Wang, Hua Zhu*, Zhi Yang*. Development of an albumin-based PSMA probe with prolonged half-life.,Frontiers in Molecular Biosciences.,2020, 7. 585024.

王风, 郭晓轶, 刘特立, 丁立新,夏雷,丁缙,蒋金泉,朱华,杨志. 固体靶PET核素89Zr的制备、质量控制和抗体标记,中华核医学与分子影像杂志. DOI: 10.3760/cma.j.cn321828-20191018-00226,,2020,40 (05): 294-297

马圆,王风,韩勇,张凤,梁志刚,黄健,杨志*,郭秀花*.基于深度信念网络检测PET/CT图像肺结节良恶性.,中国医学影像技术,,2020,36(1):77~80

Yan-Qing Liu, Zhi Yang, Yan-Song Lin*. Reactions to COVID-19: actions of nuclear medicine healthcare personnel in China.,Eur J Nucl Med Mol Imaging.,2020, DOI 10.1007/s00259-020-04857-0.

兰晓莉,高再荣,杨志,李思进*,李亚明*. 2019新型冠状病毒感染疫情期间核医学诊疗安全防控专家共识(第一版).,中华核医学与分子影像杂志.,2020, 40(3), 129-134.

王风,朱华,李立强,郭晓轶,刘特立,杨志*. 新型固体靶核素Zr-89的制备、标记和临床前应用研究进展,同位素.,2020, 33(2): 117-123

Teli Liu, Chen Liu, Xiaoxia Xu, Fei Liu, Xiaoyi Guo, Nan Li, Xuejuan Wang, Jianhua Yang, Xing Yang, Hua Zhu*, Zhi Yang*. Preclinical evaluation and primary clinical study of Al18F-PSMA-BCH in PET imaging of prostate cancer.,Journal of Nuclear Medicine,2019, 60:1284-1292.

Qian Yu#, Lixin Wang#, Jin Ding, Zhi Yang, Chengchao Shou, Chuanke Zhao*, Hua Zhu*. Evaluation of 111In-DOTA-F56 peptide targeting VEGFR1 for potential non-invasive Gastric Cancer xenografted tumor mice Micro-SPECT imaging.,Bioorganic & Medicinal Chemistry Letters.,2020, 30, 127248

Xudong Wang#, Feng Wang#, Jintao Han, Zhi Yang, Hua Zhu,* Gen Yang*. Construction and Preclinical Evaluation of a 124/131I?Labeled Radiotracer for the Detection of Mesothelin-Overexpressing Cancer.,Molecular Pharmaceutics.,2020 Jun 1;17(6):1875-1883.Epub 2020 May 9

Song Jinling, Li Zhongwu, Chen Puyun, Zhou Nina, Zhang Yan, Yang Zhi,Wang Xuejuan. The correlation between molecular pathological profiles and metabolic parameters of (18)F-FDG PET/CT in patients with gastroesophageal junction cancer,[Abdominal radiology (New York),2020, 45(2): 312-321.

Xianteng Yang#, Hua Zhu#, Xing Yang, Chaoyong Deng, Nan Li, Haifeng Huang, Teli Liu, Xiaoyi Guo, Xiaoxia Xu, Lei xia, Xiaobin Tian*, Zhi Yang*. Targeting CAIX with [64Cu]XYIMSR-06 small molecular radio-tracer enables non-invasive PET imaging of malignant glioma in U87 MG tumor cell xenograft mice.,Mol. Pharmaceutics,2019, 16, 1532-1540.

Fei Liu, Xiaoyi Guo, Teli Liu, Xiaoxia Xu, Nan Li, Chiyi Xiong, Chun Li, Hua Zhu,* Zhi Yang*. 64Cu-Labeled pan-SSTRs Targeted Precursor PA1 for Micro-Positron Emission Tomography Imaging.,ACS Medicinal Chemistry Letters.,2020. DOI: 10.1021/acsmedchemlett.9b00544. (Q2, SCI 3.74).

Xun Feng, Yanpu Wang, Dehua Lu, Xiaoxia Xu, Xin Zhou, Huiyuan Zhang, Ting Zhang, Hua Zhu, Zhi Yang, Fan Wang, Nan Li*, Zhaofei Liu*. Clinical Translation of a 68Ga-labeled Integrin αvβ6-targeting Cyclic Radiotracer for PET Imaging of Pancreatic Cancer,Journal of Nuclear Medicine,,2020. doi:10.2967/jnumed.119.237347

Chen Liu#, Teli Liu#, Zhongyi Zhang#, Ning Zhang, Peng Du, Yong Yang, Yiqiang Liu, Wei Yu, Nan Li, Michael A Gorin, Steven P. Rowe*, Hua Zhu*, Kun Yan*, Zhi Yang*. PSMA PET/CT and standard plus PET/CT-Ultrasound fusion targeted prostate biopsy can diagnose clinically significant prostate cancer in men with previous negative biopsies.,Journal of Nuclear Medicine,2020-Feb-07 (Epub 2020 Feb 07)

Jinquan Jiang#, Meixin Zhang#, Guanghui Li, Teli Liu, Zhaofei Liu, Yakun Wan, Hua Zhu*, Zhi Yang*. Evaluation of 64Cu radiolabeled anti-hPD-L1 Nb6 for positron emission tomography imaging in lung cancer tumor mice model.,Bioorganic & Medicinal Chemistry Letters. 2020,2020, 30(4), 126915. (Q2, SCI 2.442)

Xiaoxia Xu#, Hua Zhu#, Fei Liu, Yan Zhang, Jianhua Yang, Lifang Zhang, Qing Xie, Lin Zhu, Nan Li*, Hank F. Kung*, Zhi Yang*. Dynamic PET/CT imaging of 18F-(2S, 4R)4-fluoroglutamine in healthy volunteers and oncological patients.,European Journal of Nuclear Medicine and Molecular Imaging,,PMID: 32166510 DOI: 10.1007/s00259-019-04543-w

Hua Zhu#, Teli Liu#, Changhao Liu, Jing Wang, Hong Zhang, Bin Dong, Jing Shen, Chuanke Zhao, Zhenfu Li, Zhen Cheng*, Zhi Yang*. Evaluation of a novel monoclonal antibody mAb109 by immuno-PET/fluorescent imaging for noninvasive lung adenocarcinoma diagnosis.,Acta Pharmacologica Sinica.,2020. 41, 101-109. (SCI IF 4.0 Q1 )

王淑静,徐晓霞,周欣,刘特立,李囡,朱华*,杨志*. 肿瘤免疫治疗PD-1/PD-L1靶向核素分子探针的研究进展.,肿瘤防治研究.,2020, 47(01): 70-76.

王风,王磊,李囡,杨志,基于三维卷积神经网络深度学习的肺结节良恶性的鉴别诊断,,中国医学影像学杂志,2019,27(10):779-782+787.

黄海峰, 朱华, 杨先腾, 郭晓轶, 李姗姗, 谢泉, 田晓斌*, 杨志*. 恶性骨肿瘤中程序性死亡蛋白1及其配体的临床研究进展.,中华肿瘤杂志,,2019, 41(6), 410-414.

周妮娜,于江媛,朱华,赵伟,杨志.腹部纤维母细胞/肌纤维母细胞性肿瘤的PET/CT影像学特点及其应用价值.,肿瘤防治研究.,2019,46(3):243-247.

刘特立,刘辰,夏雷,郭晓轶,蒋金泉,朱华,李囡,王铁*,杨志*.PSMA分子探针Al18F-PSMA-BCH的制备及其临床应用.,中华核医学与分子影像杂志.,2019,39(12):743-747

刘辰,刘特立,杨志,张宁,杜鹏,杨勇,刘毅强,王静,严昆,杨兴,朱华,李囡*. 68Ga-PSMA-617 PET/CT对高危前列腺癌的预测价值.,中华核医学与分子影像杂志,2019,39(2):77-80.

蒋金泉, 刘特立, 夏雷, 朱华*, 杨志. 小分子肽免疫检查点抑制剂PET探针引导肿瘤免疫治疗新进展.,国际肿瘤学杂志,2019, 46(8), 449-452.

周妮娜,朱华,杨志.靶向HER2阳性肿瘤的PET/CT分子显像临床研究进展,肿瘤防治研究.,2019,46(04):376-381.

朱华, 刘特立, 王风, 蒋金泉, 韩雪迪, 杨志*. 64Cu标记DKFZ-PSMA-617探针的制备、质控及体内分布的研究,[J]. 同位素,,2019, 32(6), 382-387.

张美欣, 刘特立, 郭晓轶, 徐晓霞, 朱华*, 杨志.单域抗体在肿瘤分子影像学中的研究进展,肿瘤防治研究,2019, 46(03): 262-265.

郭晓轶,周妮娜,刘特立,徐晓霞,夏雷,朱华*,杨志*. 分子影像引导HER2阳性肿瘤诊疗新进展,肿瘤防治研究,2019. 46(6), 551-555.

Chen Liu#, Teli Liu#, Jingjing Zhang, Richard P. Baum, Zhi Yang*. Excellent Response to Lu-177-DOTATATE PRRT in a Patient with Progressive Metastatic Castration-Resistant Prostate Cancer (mCRPC) with Neuroendocrine Differentiation After Lu-177-PSMA Therapy.,Clinical Nuclear Medicine,2019 44: 876-878. (SCI IF 6.5 Q1 )

Lei Xia, Xiaoyi Guo, Teli Liu, Xiaoxia Xu, Jinquan Jiang, Feng Wang, Zhen Cheng, Hua Zhu*, Zhi Yang*. Multimodality Imaging of Naturally Active Melanin Nanoparticles Targeting Somatostatin Receptor Subtype 2 in Human Small-Cell Lung Cancer.,Nanoscale. 2019, 11, 14400-14409. (Q1, SCI 7.23),2019, 11, 14400-14409.

43. Xiaoyi Guo?, Hua Zhu?, Teli Liu, Xiaoxia Xu, Yan Kong, Sheng Yao, Xinan Sheng*, Zhi Yang*. Development of 99mTc-conjugated JS001 antibody for in vivo mapping of PD-1 distribution in murine.,Bioorganic & Medicinal Chemistry Letters. 2019. 25(16), 2178-2181 . (Q2, SCI 2.442),2019. 25(16), 2178-2181 .

Rui Bao, Yanpu Wang, Jianhao Lai, Hua Zhu, Yang Zhao, Suping Li, Nan Li,* Jing Huang, Zhi Yang,* Fan Wang, and Zhaofei Liu*.Enhancing Anti-PD-1/PD-L1 Immune Checkpoint Inhibitory Cancer Therapy by CD276-Targeted Photodynamic Ablation of Tumor Cells and Tumor Vasculature.,Mol. Pharmaceutics,2019, 16, 339-348.

Xianteng Yang#, Fan Wang#, Hua Zhu; Zhi Yang*, TaiWei Chu*. Synthesis and bioevaluation of novel 18FDG-conjugated 2-nitroimidazole derivatives for tumor- hypoxia imaging.,Mol. Pharmaceutics,2019, 16, 2118-2128.

Hua Zhu#, Teli Liu#, Changhao Liu, Jing Wang, Hong Zhang, Bin Dong, Jing Shen, Chuanke Zhao, Zhenfu Li, Zhen Cheng*, Zhi Yang*. Evaluation of a novel monoclonal antibody mAb109 by immuno-PET/fluorescent imaging or noninvasive lung adenocarcinoma diagnosis. Acta Pharmacologica Sinica.,Acta Pharmacologica Sinica,2020;41(1):101–109.

Jiangyuan Yu, Nan Li, Jie Li, Ming Lu, Jeffrey P. Leal, Huangying Tan, Hua Su, Yang Fan, Yan Zhang, Wei Zhao, Hua Zhu, Martin G. Pomper, Yun Zhou* , Zhi Yang*. The Correlation between [68Ga]DOTATATE PET/CTand Cell Proliferation in Patients with GEP-NENs.,Molecular Imaging and Biology.,2019. 21: 984-990.

夏雷, 程震, 朱华*, 杨志*. 124I原位标记有机黑色素纳米粒子的制备及初步分子影像研究.,化学学报,2019, Vol. 77 Issue (2): 172-178.

郭锐, 李囡, 王菲, 范洋, 赵伟 杨志*. ~(18)F-FDG PET/CT在同时性多原发癌中的应用 [J].,肿瘤 ,2018, 04): 371-378.

郭锐, 李囡, 方志伟, 苏华, 王菲 杨志*. ~(18)F-FDG PET/CT在骨破坏鉴别诊断中的应用 [J].,中华肿瘤防治杂志 , 2018, 25(08): 581-585.

Wang Feng, Liu Teli, Li Liqiang, Guo Xiaoyi, Duan Dongban, Liu Zhibo, Zhu Hua Yang Zhi*. Production, quality control of next-generation PET radioisotope iodine-124 and its thyroid imaging [J]. Journal of Radioanalytical and Nuclear Chemistry 2018.,Journal of Radioanalytical and Nuclear Chemistry 2018.,First Online: 27 October 2018

C Liu, TL Liu, N Zhang, YQ Liu, N Li, P Du, Y Yang, M Liu, K Gong, X Yang, H Zhu*, K Yan, Z Yang*. 68Ga-PSMA-617 PET/CT: a promising new technique for predicting risk stratification and metastatic risk of prostate cancer patients,European Journal of Nuclear Medicine and Molecular Imaging,,2018, (DOI: 10.1007/s00259-018-4037-9)

Xiaoxia Xu, Teli Liu, Fei Liu, Xiaoyi Guo, Lei Xia, Qing Xie, Nan Li, Haifeng Huang, X imianteng Yang, Yangchun Xin, Hua Zhu*, Zhi Yang*.Synthesis and evaluation of 64Cu-radiolabeled NOTA-cetuximab for immuno-PET imaging of EGFR expression.,Chinese Journal of Cancer Research.,2019, 31(2):400-409. (Q2, SCI 3.69)

Xie QH†, Zhu H†, Wang F, Meng XX, Ren QS, Xia CQ *, Yang Z*.Establishing Reliable 64Cu Production Process: From Target Plating to Molecular Specific Tumor Micro-PET Imaging,Molecules ,2017, 22, 641 (doi:10.3390/molecules22040641).

F Liu#, H Zhu#, JY Yu, XD Han, QH Xie, TL Liu, CQ Xia, N Li*, Z Yang*. 68Ga/177Lu-labeled DOTA-TATE show similar imaging andbiodistribution in neuroendocrine tumor model.,Tumor Biology ,TUBI-D-16-04135

Novel 18F-labeled 1-Hydroxyanthraquinone derivatives for necrotic myocardium imaging ,ACS Med Chem Lett ,2017;8(2):191-195

125I-F56 Peptide as Radioanalysis Agent Targeting VEGFR1 in Mice Xenografted with Human Gastric Tumor. ,ACS Med Chem Lett ,2017;8:266-269

朱华, 李一林, 赵传科, 解清华, 刘菲, 韩雪迪, 高静, 夏传琴, 沈琳*, 杨志*. 64Cu-NOTA-Herceptin的设计、活性测定及肿瘤靶向分子显像的研究,高等学校化学学报 ,2016. 37, 2132-2137

Nan Li†, Hua Zhu†, Yan Li, Jing Wang, Zhi Yang*. Synthesis and evaluation of Cy5.5-Rit tracer for specific near-infrared fluorescence imaging of sentinel lymph node.,Bioorganic & Medicinal Chemistry Letters. ,2016, 26, 4233-4236.

Wu Y†, Zhu H†, Zhang B, Liu F, Chen J, Wang Y, Wang Y, Zhang Z, Wu L, Si L, Xu H, Yao T, Xiao S, Xia Q, Zhang L, Yang Z*, Zhou D*. Synthesis of Site-Specific Radiolabeled Antibodies for Radioimmunotherapy via Genetic Code Expansion.,Bioconjug Chem ,2016, 27(10), 2460–2468.

Xianteng Yang?, Hua Zhu?, Xing Yang, Chaoyong Deng, Nan Li, Haifeng Huang, Teli Liu, Xiaoyi Guo, Xiaoxia Xu, Lei xia, Xiaobin Tian*, Zhi Yang*. Targeting CAIX with [64Cu]XYIMSR-06 small molecular radio-tracer enables non-invasive PET imaging of malignant glioma in U87 MG tumor cell xenograft mice.,Mol. Pharmaceutics,2019, 16, 1532-1540. (SCI IF 4.556 Q1 )

Hua Zhu, Liu Fei, Yan Zhang, Jianhua Yang, Xiaoxia Xu, Xiaoyi Guo, Teli Liu, Nan Li, Lin Zhu, Hank F. Kung*, Zhi Yang*. [18F](2S,4R)-4-Fluoroglutamine as a PET indicator for bone marrow metabolism dysfunctional: From animal experiments to clinical application.,Molecular Imaging and Biology.,2019. 21:945-953. (Q1, SCI 3.626)

淋巴瘤PET/CT影像学, 参编 , 人民卫生出版社, 2017.5

前列腺癌精准诊断与治疗, 参编 , 人民卫生出版社, 2019.5

《核医学名词》, 参编 , 科学出版社, 2019.4

《核医学进展(2014-2016)》, 参编 , 中国医学电子音像出版社, 2018.4

原发性乳腺癌腋窝淋巴结处理路径创新与应用, 华夏医学科技奖 三等奖, 第2完成人 , 华夏医学科技奖 三等奖, 2018.4

2020年度中华医学会核医学分会突出贡献奖, 突出贡献奖, 第2完成人 , 中华医学会核医学分会, 2020.9

正电子发射断层(PET)显像的技术创新及转化应用, 中华医学科技奖 二等奖, 第4完成人 , 中华医学会, 2019.12

北京大学医学部良师益友奖, 北京大学医学部良师益友奖, 第1完成人 , 北京大学医学部, 2018.9

18F-(2S ,4R)-4-氟-L-谷胺酰胺的自动化生产设备, 发明专利, 第1完成人 , 中华人民共和国专利局, 中国, 2020.3

一种可在线监测的小型回旋加速器固体靶电镀装置。实用新型专利,授权日:2017-05-03, 实用新型, 第4完成人 , 中华人民共和国专利局, 中国, 2017.5

一种放射性核素标记的特异性前哨淋巴结显像剂及其制备方法, 发明专利, 第1完成人 , 中华人民共和国专利局, , 2017.10

Al18F标记的PSMA靶向抑制剂及其制备方法与应用, 发明专利, 第1完成人 , 中华人民共和国专利局, 中国, 2018.6

神经内分泌肿瘤靶向纳米粒子显像剂及其制备方法的专利, , 第1完成人 , 中华人民共和国专利局 , , 2018.6

核素标记的前列腺特异性膜抗原靶向抑制剂及其制备方法的专利, , 第1完成人 , 中华人民共和国专利局 , , 2018.6

登峰人才计划:核医学(杨志), 课题负责人 , 2020.1.1~2023.12.31, 登峰人才计划

肿瘤核医学精准诊疗一体化研究论坛, 课题负责人 , 2020.5.1~2020.12.31, 北京市自然科学基金

肿瘤核医学专业, 课题负责人 , 2018.1.4~2020.12.31, 扬帆计划-重点医学专业

A2δ1亚基阳性特异性PET探针的构建及在肝癌干细胞诊疗的研究, 课题负责人 , 2019.1.1~2022.12.31, 国家自然科学基金

基于复轮廓波变换提取多模态影像纹理及相关因素构建深度信念网络肺癌早期诊断模型, 子课题负责人 , 2018.9.1~2020.9.30, 国家自然科学基金

18F-氟代谷氨酰胺探针的肿瘤氨基酸代谢显像及其与 Myc 基因调控相关机制的研究, 课题负责人 , 2017.1.7~2020.12.31, 2017年 北京市自然科学基金 重点项目 7171002

前列腺癌PSMA靶向PET探针的开发及临床转化研究, 课题负责人 , 2020.1.1~2020.12.31, 北京大学肿瘤医院

89Zr-CTB006单克隆抗体的制备、质控研究, 课题负责人 , 2019.3.1~2020.12.31, 北京先通生物医药技术有限公司

PET分子探针在淀粉样脑血管病诊断中的临床研究, 课题负责人 , 2019.1.1~2020.12.31, 首都医科大学附属北京天坛医院

核素/红外双模特意SLN探针的构建, 课题负责人 , 2018.1.4~2019.12.31, 论文奖励

乳腺专用低剂量多能CT技术研究, 子课题负责人 , 2016.7.1~2018.12.31, 2016年国家重点研发计划 申报编号:SQ2016ZY04002762

靶向生长抑素受体各亚型的68Ga/177Lu-PA探针的构建及其在肿瘤个体化诊疗中的研究, 课题负责人 , 2016.1.1~2019.12.31, 2015年 国家自然科学基金 编号 NO 881571705

铜-64标记的双硝基咪唑乏氧分子探针的构建及其在肿瘤乏氧诊疗中的应用研究, 课题负责人 , 2014.1.1~2017.12.31, 2013年 国家自然科学基金 81371592

研究生招生计划
招生年度 招生专业 学位级别 学位类型 研究方向 选拔方式
2022 影像医学与核医学 硕士 科学学位 新型放射性药物的研究 全国统考
2022 影像医学与核医学 博士 科学学位 肿瘤靶向放射性药物研究及转化 申请考核制

社会任职

  • Cancer Biotherapy and Radiopharmaceuticals the editorial board as Associate Editor of Asia
  • 《中华核医学与分子影像杂志》常务编委
  • 《肿瘤影像学》杂志副主编
  • 中国医学影像技术研究会理事
  • 中国核学会核化学与放射化学分会理事

学习、工作经历

  • 2009.6.1~2020.1.13,2009/06-至今,北京大学医学部核医学系副主任
  • 2006.9.1~2009.6.30,中国原子能科学研究院,放射性同位素应用专业,工学博士
  • 2005.10.1~2007.11.30,美国德州大学,MD Anderson肿瘤中实验影像诊断系,访问学者
  • 2000.9.1~2003.7.31,北京大学,技术物理系核技术应用专业 ,硕士
  • 1992.12.31~2020.1.13,北京市肿瘤防治研究所(北京肿瘤医院),核医学科,研究实习员、助理研究员副研究员、研究员、副主任、主任