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导师基本信息

  • 姓名:吴楠
  • 性别:
  • 民族:汉族
  • 科室:胸外科二病区
  • 职称:主任医师,教授
  • 专业:肿瘤学、肿瘤外科学
  • E-MAIL: nanwu@bjmu.edu.cn

学术论文 | 出版专著 | 奖励表彰 | 研究方向 | 专利 | 科研项目 | 招生计划

Lv C#, Lu F#, Zhou X#, Li X#, Yu W, Zhang C, Chen K, Du S, Han C, Wang J, Wang Y, Li S, Wang L, Liu Y, Zhang S, Huang M, Song D, Zhao D, Liu B, Wang Y, Cui X, Zhou Z, Yan S, Wu N*. Efficacy of a smartphone application assisting home-based rehabilitation and symptom management for patients with lung cancer undergoing video-assisted thoracoscopic lobectomy: a prospective, single-blinded, randomised control trial (POPPER study).,International Journal of Surgery,2024 Jun 21

Dong Z#, Wang Y#, Xu G#, Liu B#, Wang Y, Reboud J, Jajesniak P, Yan S, Ma P, Liu F, Zhou Y, Jin Z, Yang K, Huang Z, Zhuo M, Jia B, Fang J, Zhang P, Wu N*, Yang M*, Cooper JM*, Chang L*. Genetic and phenotypic profiling of single living circulating tumor cells from patients with microfluidics.,PNAS,2024 May 7;121(19):e2315168121

Yin S#, Yu Y#, Wu N#, Zhuo M, Wang Y, Niu Y, Ni Y, Hu F, Ding C, Liu H, Cheng X, Peng J, Li J, He Y, Li J, Wang J, Zhang H, Zhai X, Liu B, Wang Y, Yan S, Chen M, Li W, Peng J, Peng F, Xi R, Ye B*, Jiang L*, Xi JJ*. Patient-derived tumor-like cell clusters for personalized chemo- and immunotherapies in non-small cell lung cancer.,Cell Stem Cell,2024 May 2;31(5):717-733.e8

Liu Y#, Wang Y#, Liu B, Liu W, Ma Y, Cao Y, Yan S, Zhang P, Zhou L, Zhan Q*, Wu N*.Targeting lncRNA16 by GalNAc-siRNA conjugates facilitates chemotherapeutic sensibilization via the HBB/NDUFAF5/ROS pathway.,Science China Life Sciences,2024 Apr;67(4):663-679

Danqing Hu*, Bing Liu, Xiaofeng Zhu*, Xudong Lu, Nan Wu*. Zero-shot information extraction from radiological reports using ChatGPT.,International Journal of Medical Informatics,2024 Mar:183:105321

Yan Wang#, Bing Liu#, Qingjie Min#, Xin Yang#, Shi Yan, Yuanyuan Ma, Shaolei li, Jiawen Fan, Yagi Wang,Bin Dong, Huajing Teng, Dongmei Lin, Qimin Zhan* and Nan Wu*. Spatial transcriptomics delineates molecularfeatures and cellular plasticity in lungadenocarcinoma progression,Cell Discovery,2023 Sep 19;9(1):96

Li X#, Zhang S#, Luo X, Gao G, Luo X, Wang S, Li S, Zhao D, Wang Y, Cui X, Liu B, Tao Y, Xiao B, Tang L, Yan S*, Wu N*. Accuracy and efficiency of an artificial intelligence-based pulmonary broncho-vascular three-dimensional reconstruction system supporting thoracic surgery: Retrospective and prospective validation study,eBioMedicine,2023 Jan;87:104422

Xuantong Zhou#, Furong Huang#, Gang Ma#, Wenqing Wei, Nan Wu* and Zhihua Liu*. Dysregulated ceramides metabolism by fatty acid 2-hydroxylase exposes a metabolic vulnerability to target cancer metastasis,Signal Transduction and Targeted Therapy,2022 Oct 24;7(1):370

Ma Y#, Kang B#, Li S#, Xie G#, Bi J, Li F, An G, Liu B, Li J, Shen Y, Xu X, Yang H, Yang Y*, Gu Y*, Wu N*. CRISPR-mediated MECOM depletion retards tumor growth by reducing cancer stem cell properties in lung squamous cell carcinoma,Molecular Therapy,2022 Nov 2;30(11):3341-3357

Li J#, Liu B#, Ye Q#, Xiao X, Yan S, Guan W, He L, Wang C, Yu Z, Tai Z, Pei S, Ma Y, Li S, Wang Y, Wu N. Comprehensive genomic analysis of primary malignant melanoma of the esophagus reveals similar genetic patterns compared with epithelium-associated melanomas,Modern Pathology,2022 Nov;35(11):1596-1608

Shen L#, Xiao Y#, Zhang C, Li S, Teng X, Cui L, Liu T, Wu N*, Lu Z*. Metabolic reprogramming by ex vivo glutamine inhibition endows CAR-T cells with less-differentiated phenotype and persistent antitumor activity,Cancer Lett,2022 Jul 10;538:215710

Hu D#, Li S#, Wu N*, Lu X*. A Multi-modal Heterogeneous Graph Forest to Predict Lymph Node Metastasis of Non-small Cell Lung Cancer,IEEE J Biomed Health Inform,2023 Jan 2;PP

Xiao BF#, Zhang JT#, Zhu YG#, Cui XR, Lu ZM, Yu BT*, Wu N*. Chimeric Antigen Receptor T-Cell Therapy in Lung Cancer: Potential and Challenges,Frontiers In Immunology,2021 Nov 1;12:782775

Dong Z#, Yan S#, Liu B, Hao Y, Lin L, Chang T, Sun H, Wang Y, Li H, Wu H, Hang X, He S, Hu J, Xue X*, Wu N*, Chang L*. Single Living Cell Analysis Nanoplatform for High-Throughput Interrogation of Gene Mutation and Cellular Behavior. Nano Lett.,Nano letters,2021 Jun 9;21(11):4878-4886

Juntuo Zhou, Bing Liu, Zhongwu Li3, Yang Li4, Xi Chen4, Yuanyuan Ma1, Shi Yan1, Xin Yang3, Lijun Zhong5,# and Nan Wu. Proteomic analyses identify differentially expressed proteins and pathways between low-risk and high-risk subtypes of early-stage lung adenocarcinoma and their prognostic impacts,Molecular Cellular Proteomics,

Wang X#, Zhang L#, Yang X#, Tang L#, Zhao J, Chen G, Li X, Yan S, Li S, Yang Y, Kang Y, Li Q*, Wu N*. Deep learning combined with radiomics may optimize the prediction in differentiating high-grade lung adenocarcinomas in ground glass opacity lesions on CT scans.,European Journal of Radiology,2020 Aug:129:109150

Shaolei Li#,Mailin Chen#, Yaqi Wang, Xiang Li, Guangming Gao, Xiangfeng Luo, Lei Tang, Xiaohua Liu, Nan Wu. An Effective Malignancy Prediction Model for Incidentally Detected Pulmonary Subsolid Nodules Based on Current and Prior CT Scans.,Clinical Lung Research,Volume 24, Issue 8, December 2023, Pages e301-e310

Xinrun Cui#, Xiang Li#, Chao Lv, Shi Yan, Jia Wang, Nan Wu*. Efficacy and safety of adjuvant EGFR TKI alone and in combination with chemotherapy for resected EGFR mutation-positive non-small cell lung cancer: A Bayesian network meta-analysis.,Critical Reviews in Oncology/Hematology,Volume 186, June 2023, 104010

Hu D, Zhang H, Li S, Duan H, Wu N*, Lu X*. An ensemble learning with active sampling to predict the prognosis of postoperative non-small cell lung cancer patients,BMC Med Inform Decis Mak,2022 Sep 19;22(1):245

Wang Y#, Pei Y#, Lv C, Wang Y, Wang J, Zhao D, Li X, Yang Y, Kim AW, Toker A, Yan S*, Wu N*. Intermittent chest tube clamping decreases chest tube duration time and drainage volume after lung cancer surgery in patients without air leak: an open-label, randomized controlled trial,Transl Lung Cancer Res,2022 Mar;11(3):357-365

Wang Y#, Yang X#, Liu B, Yan S, Liu M, Li X, Li S, Lv C, Ma Y, Zhou L, Song Z, Xv W, Yang Y, Lin D*, Wu N*. Percentage of Newly Proposed High-Grade Patterns Is Associated with Prognosis of Pathological T1-2N0M0 Lung Adenocarcinoma,Ann Surg Oncol,2022 Feb 24

Shaolei Li, Shi Yan, Fangliang Lu, Chao Lv, Yaqi Wang, Xiang Li, Yuzhao Wang, Yue Yang & Nan Wu. Validation of the 8th Edition Nodal Staging and Proposal of New Nodal Categories for Future Editions of the TNM Classification of Non-Small Cell Lung Cancer.,ANNALS OF SURGICAL ONCOLOGY,

Nan Wu, Sixue Liu, Jingjing Li, Zhenyu Hu, Shi Yan, Hongwei Duan, Dafei Wu, Yuanyuan Ma, Shaolei Li, Xing Wang, Yaqi Wang, Xiang Li, Xuemei Lu. Deep sequencing reveals the genomic characteristics of lung adenocarcinoma presenting as ground-glass nodules (GGNs),Translational Lung Cancer Research,

Xiang Li,Shi Yan,Yuanyuan Ma,Shaolei Li,Yaqi Wang,Xing Wang,Yuzhao Wang,Jia Wang,Chao Lv,Yue Yang,NanWu Impact of Early Oral Feeding on Anastomotic Leakage Rate After Esophagectomy: A Systematic Review and Meta-analysis,World J Surg,

Huang M#, Liu B#, Li X, Li N, Yang X, Wang Y, Zhang S, Lu F, Li S, Yan S, Wu N*. Beneficial implications of adjuvant chemotherapy for stage IB lung adenocarcinoma exhibiting elevated SUVmax in FDG-PET/CT: a retrospective study from a single center.,Frontiers in Oncology,2024 Mar 11:14:1367200

Tao Y, Li X, Liu B, Wang J, Lv C, Li S, Wang Y, Chen J, Yan S*, Wu N*. Association of early immune-related adverse events with treatment efficacy of neoadjuvant Toripalimab in resectable advanced non-small cell lung cancer.,Frontiers in Oncology,2023 May 15:13:1135140

Liu B, Wang C, Fang Z, Bai J, Qian Y, Ma Y, Ruan X, Yan S, Li S, Wang Y, DongB, YangX, LiM, XiaX, QuH, FangX and Wu N. Single-cell RNA sequencing reveals the cellular and molecular changes that contribute to the progression of lung adenocarcinoma,Frontiers in Cell and Developmental Biology,2022;10:927300

Liu B#, Wang Y#, Wang H, Li Z, Yang L, Yan S, Yang X, Ma Y, Gao X, Guan Y, Yi X, Xia X*, Li J*, Wu N*. RBM10 Deficiency Is Associated With Increased Immune Activity in Lung Adenocarcinoma,Frontiers in Oncology,2021 Jul 21;11:677826

Xiang Li, Shi Yan, Jichun Yang, Yaqi Wang, Chao Lv, Shaolei Li, Jun Zhao, Yue Yang, Minglei Zhuo and Nan Wu . Efficacy and Safety of PD-1/PD-L1 Inhibitors Plus Chemotherapy Versus PD-1/PD-L1 Inhibitors in Advanced Non-Small Cell Lung Cancer: A Network Analysis of Randomized Controlled Trials,Frontiers in Oncology,

Danqing Hu,Shaolei Li,Zhengxing Huang,Nan Wu,Xudong Lu. Predicting postoperative non-small cell lung cancer prognosis via long short-term relational regularization,Artificial Intelligence in Medicine,Volume 107

Zhang H#, Hu D#, Duan H, Li S, Wu N*, Lu X*. A novel deep learning approach to extract Chinese clinical entities for lung cancer screening and staging,BMC Medical Informatics and Decision Making,2021 Jul 30;21(Suppl 2):214

Jun Ni#, Miao Huang#, Li Zhang*, Nan Wu* et al.Clinical recommendations for perioperative immunotherapy- induced adverse events in patients with non-small cell lung cancer,Thoracic Cancer,2021 May;12(9):1469-1488

倪军#, 黄淼#, 张力*, 吴楠*等. 非小细胞肺癌围手术期免疫治疗相关不良反应管理的临床诊疗建议,中国肺癌杂志,2021,24(3):141-160

赵大川, 阎石, 王亚旗, 马媛媛, 王兴, 李少雷, 李想, 吕超, 王宇昭, 王嘉, 杨跃, 吴楠. N1 期非小细胞肺癌患者肺内转移淋巴结解剖部位与疾病复发风险及预后的关系分析,中华医学杂志,2021, 101(35): 2778-2786

阎石,吴楠. 基于非小细胞肺癌系统性肺内淋巴结清扫的N1分期改良建议,中华医学杂志,2021,101(35):2748-2750

郏博, 吕超, 常建华, 吴楠*, 王子平*等. 非小细胞肺癌非常见突变靶向治疗研究进展,中华医学杂志,2022, 102(13) : 969-976

社会任职

  • 国际肺癌研究协会(IASLC)会员委员会委员、前任主席
  • 欧洲肺癌大会(ELCC) 学术委员会委员
  • 亚洲临床肿瘤联盟(FACO)肺癌学术委员会委员
  • 中国临床肿瘤学会智慧医疗专家委员会 副主任委员
  • 中华医学会肿瘤学分会 委员

学习、工作经历

  • 2023.11.1~,北京大学肿瘤医院云南医院执行院长
  • 2022.6.1~,北京大学肿瘤医院副院长
  • 2018.3.11~2019.9.11,中组部第八批援藏干部,在西藏大学医院院任常务副院长、院长
  • 2016.8.1~,北京大学肿瘤医院胸部肿瘤中心副主任
  • 2004.4.12~,北京大学肿瘤医院胸外科