Lv C#, Lu F#, Zhou X#, Li X#, Yu W, Zhang C, Chen K, Du S, Han C, Wang J, Wang Y, Li S, Wang L, Liu Y, Zhang S, Huang M, Song D, Zhao D, Liu B, Wang Y, Cui X, Zhou Z, Yan S, Wu N*. Efficacy of a smartphone application assisting home-based rehabilitation and symptom management for patients with lung cancer undergoing video-assisted thoracoscopic lobectomy: a prospective, single-blinded, randomised control trial (POPPER study).,International Journal of Surgery,2024 Jun 21

Dong Z#, Wang Y#, Xu G#, Liu B#, Wang Y, Reboud J, Jajesniak P, Yan S, Ma P, Liu F, Zhou Y, Jin Z, Yang K, Huang Z, Zhuo M, Jia B, Fang J, Zhang P, Wu N*, Yang M*, Cooper JM*, Chang L*. Genetic and phenotypic profiling of single living circulating tumor cells from patients with microfluidics.,PNAS,2024 May 7;121(19):e2315168121

Yin S#, Yu Y#, Wu N#, Zhuo M, Wang Y, Niu Y, Ni Y, Hu F, Ding C, Liu H, Cheng X, Peng J, Li J, He Y, Li J, Wang J, Zhang H, Zhai X, Liu B, Wang Y, Yan S, Chen M, Li W, Peng J, Peng F, Xi R, Ye B*, Jiang L*, Xi JJ*. Patient-derived tumor-like cell clusters for personalized chemo- and immunotherapies in non-small cell lung cancer.,Cell Stem Cell,2024 May 2;31(5):717-733.e8

Liu Y#, Wang Y#, Liu B, Liu W, Ma Y, Cao Y, Yan S, Zhang P, Zhou L, Zhan Q*, Wu N*.Targeting lncRNA16 by GalNAc-siRNA conjugates facilitates chemotherapeutic sensibilization via the HBB/NDUFAF5/ROS pathway.,Science China Life Sciences,2024 Apr;67(4):663-679

Danqing Hu*, Bing Liu, Xiaofeng Zhu*, Xudong Lu, Nan Wu*. Zero-shot information extraction from radiological reports using ChatGPT.,International Journal of Medical Informatics,2024 Mar:183:105321

Yan Wang#, Bing Liu#, Qingjie Min#, Xin Yang#, Shi Yan, Yuanyuan Ma, Shaolei li, Jiawen Fan, Yagi Wang,Bin Dong, Huajing Teng, Dongmei Lin, Qimin Zhan* and Nan Wu*. Spatial transcriptomics delineates molecularfeatures and cellular plasticity in lungadenocarcinoma progression,Cell Discovery,2023 Sep 19;9(1):96

Li X#, Zhang S#, Luo X, Gao G, Luo X, Wang S, Li S, Zhao D, Wang Y, Cui X, Liu B, Tao Y, Xiao B, Tang L, Yan S*, Wu N*. Accuracy and efficiency of an artificial intelligence-based pulmonary broncho-vascular three-dimensional reconstruction system supporting thoracic surgery: Retrospective and prospective validation study,eBioMedicine,2023 Jan;87:104422

Xuantong Zhou#, Furong Huang#, Gang Ma#, Wenqing Wei, Nan Wu* and Zhihua Liu*. Dysregulated ceramides metabolism by fatty acid 2-hydroxylase exposes a metabolic vulnerability to target cancer metastasis,Signal Transduction and Targeted Therapy,2022 Oct 24;7(1):370

Ma Y#, Kang B#, Li S#, Xie G#, Bi J, Li F, An G, Liu B, Li J, Shen Y, Xu X, Yang H, Yang Y*, Gu Y*, Wu N*. CRISPR-mediated MECOM depletion retards tumor growth by reducing cancer stem cell properties in lung squamous cell carcinoma,Molecular Therapy,2022 Nov 2;30(11):3341-3357

Li J#, Liu B#, Ye Q#, Xiao X, Yan S, Guan W, He L, Wang C, Yu Z, Tai Z, Pei S, Ma Y, Li S, Wang Y, Wu N. Comprehensive genomic analysis of primary malignant melanoma of the esophagus reveals similar genetic patterns compared with epithelium-associated melanomas,Modern Pathology,2022 Nov;35(11):1596-1608

Shen L#, Xiao Y#, Zhang C, Li S, Teng X, Cui L, Liu T, Wu N*, Lu Z*. Metabolic reprogramming by ex vivo glutamine inhibition endows CAR-T cells with less-differentiated phenotype and persistent antitumor activity,Cancer Lett,2022 Jul 10;538:215710

Hu D#, Li S#, Wu N*, Lu X*. A Multi-modal Heterogeneous Graph Forest to Predict Lymph Node Metastasis of Non-small Cell Lung Cancer,IEEE J Biomed Health Inform,2023 Jan 2;PP

Xiao BF#, Zhang JT#, Zhu YG#, Cui XR, Lu ZM, Yu BT*, Wu N*. Chimeric Antigen Receptor T-Cell Therapy in Lung Cancer: Potential and Challenges,Frontiers In Immunology,2021 Nov 1;12:782775

Dong Z#, Yan S#, Liu B, Hao Y, Lin L, Chang T, Sun H, Wang Y, Li H, Wu H, Hang X, He S, Hu J, Xue X*, Wu N*, Chang L*. Single Living Cell Analysis Nanoplatform for High-Throughput Interrogation of Gene Mutation and Cellular Behavior. Nano Lett.,Nano letters,2021 Jun 9;21(11):4878-4886

Juntuo Zhou, Bing Liu, Zhongwu Li3, Yang Li4, Xi Chen4, Yuanyuan Ma1, Shi Yan1, Xin Yang3, Lijun Zhong5,# and Nan Wu. Proteomic analyses identify differentially expressed proteins and pathways between low-risk and high-risk subtypes of early-stage lung adenocarcinoma and their prognostic impacts,Molecular Cellular Proteomics,

Wang X#, Zhang L#, Yang X#, Tang L#, Zhao J, Chen G, Li X, Yan S, Li S, Yang Y, Kang Y, Li Q*, Wu N*. Deep learning combined with radiomics may optimize the prediction in differentiating high-grade lung adenocarcinomas in ground glass opacity lesions on CT scans.,European Journal of Radiology,2020 Aug:129:109150

Si J, Ma Y, Bi JW, Xiong Y, Lv C, Li S, Wu N, Yang Y. Shisa3 brakes resistance to EGFR-TKIs in lung adenocarcinoma by suppressing cancer stem cell properties. J Exp Clin Cancer Res.,Journal of Experimental and Clinical Cancer Research,2019 Dec 4;38(1):481

Jiahui Si, Yuanyuan Ma, Ji Wang Bi, Ying Xiong, Chao Lv, Shaolei Li, Nan Wu & Yue Yang Shisa3BrakesResistancetoEGFR-TKIsinLungAdenocarcinomabySuppressingCancerStemCellProperties,J Exp Clin Cancer Res,38: 481

Shaolei Li#，Mailin Chen#, Yaqi Wang, Xiang Li, Guangming Gao, Xiangfeng Luo, Lei Tang, Xiaohua Liu, Nan Wu. An Effective Malignancy Prediction Model for Incidentally Detected Pulmonary Subsolid Nodules Based on Current and Prior CT Scans.,Clinical Lung Research,Volume 24, Issue 8, December 2023, Pages e301-e310

Xinrun Cui#, Xiang Li#, Chao Lv, Shi Yan, Jia Wang, Nan Wu*. Efficacy and safety of adjuvant EGFR TKI alone and in combination with chemotherapy for resected EGFR mutation-positive non-small cell lung cancer: A Bayesian network meta-analysis.,Critical Reviews in Oncology/Hematology,Volume 186, June 2023, 104010

Hu D, Zhang H, Li S, Duan H, Wu N*, Lu X*. An ensemble learning with active sampling to predict the prognosis of postoperative non-small cell lung cancer patients,BMC Med Inform Decis Mak,2022 Sep 19;22(1):245

Wang Y#, Pei Y#, Lv C, Wang Y, Wang J, Zhao D, Li X, Yang Y, Kim AW, Toker A, Yan S*, Wu N*. Intermittent chest tube clamping decreases chest tube duration time and drainage volume after lung cancer surgery in patients without air leak: an open-label, randomized controlled trial,Transl Lung Cancer Res,2022 Mar;11(3):357-365

Wang Y#, Yang X#, Liu B, Yan S, Liu M, Li X, Li S, Lv C, Ma Y, Zhou L, Song Z, Xv W, Yang Y, Lin D*, Wu N*. Percentage of Newly Proposed High-Grade Patterns Is Associated with Prognosis of Pathological T1-2N0M0 Lung Adenocarcinoma,Ann Surg Oncol,2022 Feb 24

Shaolei Li, Shi Yan, Fangliang Lu, Chao Lv, Yaqi Wang, Xiang Li, Yuzhao Wang, Yue Yang & Nan Wu. Validation of the 8th Edition Nodal Staging and Proposal of New Nodal Categories for Future Editions of the TNM Classification of Non-Small Cell Lung Cancer.,ANNALS OF SURGICAL ONCOLOGY,

Nan Wu, Sixue Liu, Jingjing Li, Zhenyu Hu, Shi Yan, Hongwei Duan, Dafei Wu, Yuanyuan Ma, Shaolei Li, Xing Wang, Yaqi Wang, Xiang Li, Xuemei Lu. Deep sequencing reveals the genomic characteristics of lung adenocarcinoma presenting as ground-glass nodules (GGNs),Translational Lung Cancer Research,

Xiang Li,Shi Yan,Yuanyuan Ma,Shaolei Li,Yaqi Wang,Xing Wang,Yuzhao Wang,Jia Wang,Chao Lv,Yue Yang,NanWu Impact of Early Oral Feeding on Anastomotic Leakage Rate After Esophagectomy: A Systematic Review and Meta-analysis,World J Surg,

Huang M#, Liu B#, Li X, Li N, Yang X, Wang Y, Zhang S, Lu F, Li S, Yan S, Wu N*. Beneficial implications of adjuvant chemotherapy for stage IB lung adenocarcinoma exhibiting elevated SUVmax in FDG-PET/CT: a retrospective study from a single center.,Frontiers in Oncology,2024 Mar 11:14:1367200

Tao Y, Li X, Liu B, Wang J, Lv C, Li S, Wang Y, Chen J, Yan S*, Wu N*. Association of early immune-related adverse events with treatment efficacy of neoadjuvant Toripalimab in resectable advanced non-small cell lung cancer.,Frontiers in Oncology,2023 May 15:13:1135140

Liu B, Wang C, Fang Z, Bai J, Qian Y, Ma Y, Ruan X, Yan S, Li S, Wang Y, DongB, YangX, LiM, XiaX, QuH, FangX and Wu N. Single-cell RNA sequencing reveals the cellular and molecular changes that contribute to the progression of lung adenocarcinoma,Frontiers in Cell and Developmental Biology,2022;10:927300

Liu B#, Wang Y#, Wang H, Li Z, Yang L, Yan S, Yang X, Ma Y, Gao X, Guan Y, Yi X, Xia X*, Li J*, Wu N*. RBM10 Deficiency Is Associated With Increased Immune Activity in Lung Adenocarcinoma,Frontiers in Oncology,2021 Jul 21;11:677826

Xiang Li, Shi Yan, Jichun Yang, Yaqi Wang, Chao Lv, Shaolei Li, Jun Zhao, Yue Yang, Minglei Zhuo and Nan Wu . Efficacy and Safety of PD-1/PD-L1 Inhibitors Plus Chemotherapy Versus PD-1/PD-L1 Inhibitors in Advanced Non-Small Cell Lung Cancer: A Network Analysis of Randomized Controlled Trials,Frontiers in Oncology,

Danqing Hu,Shaolei Li,Zhengxing Huang,Nan Wu,Xudong Lu. Predicting postoperative non-small cell lung cancer prognosis via long short-term relational regularization,Artificial Intelligence in Medicine,Volume 107

Zhang H#, Hu D#, Duan H, Li S, Wu N*, Lu X*. A novel deep learning approach to extract Chinese clinical entities for lung cancer screening and staging,BMC Medical Informatics and Decision Making,2021 Jul 30;21(Suppl 2):214

Jun Ni#, Miao Huang#, Li Zhang*, Nan Wu* et al.Clinical recommendations for perioperative immunotherapy- induced adverse events in patients with non-small cell lung cancer,Thoracic Cancer,2021 May;12(9):1469-1488

倪军#, 黄淼#, 张力*, 吴楠*等. 非小细胞肺癌围手术期免疫治疗相关不良反应管理的临床诊疗建议,中国肺癌杂志,2021,24(3):141-160

赵大川, 阎石, 王亚旗, 马媛媛, 王兴, 李少雷, 李想, 吕超, 王宇昭, 王嘉, 杨跃, 吴楠. N1 期非小细胞肺癌患者肺内转移淋巴结解剖部位与疾病复发风险及预后的关系分析,中华医学杂志,2021, 101(35): 2778-2786

阎石,吴楠. 基于非小细胞肺癌系统性肺内淋巴结清扫的N1分期改良建议,中华医学杂志,2021,101(35):2748-2750

郏博, 吕超, 常建华, 吴楠*, 王子平*等. 非小细胞肺癌非常见突变靶向治疗研究进展,中华医学杂志,2022, 102(13) : 969-976

常用临床医学名词（2023年版）, 参编, 人民卫生出版社, 2024.2

临床医学概论（第3版）, 主编, 人民卫生出版社, 2023.3

《食管癌规范化手术》, 参编, 北京大学医学出版社, 2023.3

《肺癌规范化手术》, 主编, 北京大学医学出版社, 2022.12

《非小细胞肺癌非常见基因突变诊治策略》, 主编, 北京大学医学出版社, 2021.12

《老年肺癌综合治疗学》, 主编, 北京大学医学出版社, 2020.11

国家“万人计划”, 科技创新领军人才, 第1完成人, 中央人才工作协调小组, 2023.9

北京市教育系统“育人榜样（先锋）”, 教书育人先锋, 第1完成人, 北京市教育工会, 2023.5

西藏自治区优秀教育援藏人才, 西藏自治区优秀教育援藏人才, 第1完成人, 西藏自治区教育厅, 2023.1

国务院政府特殊津贴, 国务院政府特殊津贴, 第1完成人, 国务院, 2020.12

胸部肿瘤的转化研究

胸部肿瘤外科和综合治疗

一种胸腔镜镜头清洗装置, 实用新型, 第1完成人, 国家专利局, 中国, 2024.6

一种肺癌术后康复的方法及相关设备, 发明专利, 第1完成人, 国家专利局, 中国, 2024.5

一种老年肺癌患者术后短期死亡风险评估的方法及装置, 发明专利, 第1完成人, 国家专利局, 中国, 2024.1

一种层级聚类约束的多标签细粒度术后并发症预测装置, 发明专利, 第2完成人, 国家专利局, 中国, 2023.12

一种评估老年肺癌患者术后严重并发症的方法和相关设备, 发明专利, 第1完成人, 国家专利局, 中国, 2023.11

一种胸腔镜镜头防雾装置, 实用新型, 第1完成人, 国家专利局, 中国, 2023.6

silncRNA16 及其治疗铂类耐药肿瘤中的用途, 发明专利, 第2完成人, 国家专利局, 中国, 2023.6

一种锁骨下静脉穿刺置管穿刺点选择辅助装置, 实用新型, 第1完成人, 国家专利局, 中国, 2022.3

非小细胞肺癌MECOM/HBB通路介导血红素代谢异常并抑制肿瘤起始细胞铁死亡的机制研究, 课题负责人, 2023.8.24～2027.12.31, 国家自然科学基金

早期高级别肺腺癌多组学分子分型及精准治疗策略研究, 课题负责人, 2024.3.1～2026.12.31, 2024首发专项

临床高通量基因检测全自动一体化系统研发, 子课题负责人, 2022.11.1～2027.10.31, 国家重点研发计划

基于修饰蛋白组学探索早期肺腺癌发生发展机制, 课题负责人, 2023.12.1～2026.12.31, 科技创新领军人才-万人计划

基于血浆 cfDNA 多组学检测的肺癌早筛及结节风险度评模型构建, 课题负责人, 2022.12.16～2025.12.31, 北京市自然科学基金

胸部肿瘤临床与转化研究, 课题负责人, 2024.1.1～2024.12.31, 卫健委财政专项

LncRNA16抑制细胞焦亡信号通路参与非小细胞肺癌耐药机制和应用的研究, 课题负责人, 2020.6.1～2023.12.29, 国家自然科学基金面上项目

TumorX共建联合实验室, 课题负责人, 2022.7.1～2032.7.31, 无锡臻和生物科技有限公司

肺癌临床研究标准数据集, 课题负责人, 2022.11.1～2023.11.30, 北京市卫生和计划生育委员会适宜技术推广项目

登峰人才计划：胸外科学及肿瘤学（吴楠）, 课题负责人, 2020.1.1～2023.12.31, 北京市医管中心登峰

Durvalumab 联合顺铂+白蛋白结合型紫杉醇作为术前新辅助疗法用于可切除食管鳞癌的前瞻、单臂临床试验, 课题负责人, 2021.4.1～2024.3.31, CSCO

老年肺癌手术风险预测模型的构建及临床应用研究, 课题负责人, 2020.6.1～2023.5.31, 首都卫生发展科研专项

肿瘤的多学科协作临床决策支持系统研发与实践, 课题负责人, 2018.7.15～2020.12.15, 国家重点研发计划“精准医学研究”重点专项

基于标准化手术和大数据分析模拟非小细胞肺癌淋巴结转移模式的算法研究及临床应用研究, 课题负责人, 2018.1.15～2020.12.15, 北京市医管局 “扬帆计划”

NFATc2调控非小细胞肺癌肿瘤起始细胞-巨噬细胞免疫逃逸的分子机制及治疗策略, 课题负责人, 2019.1.7～2021.12.7, 北京市自然科学基金

非小细胞肺癌转移淋巴结浸润免疫细胞异质性的研究, 课题负责人, 2019.1.15～2020.12.15, 北京市人力资源和社会保障局

研究生招生计划

招生年度	招生专业	学位级别	学位类型	研究方向	选拔方式	操作
2025	肿瘤学	博士	科学学位	（医学创新交叉项目）胸部肿瘤转化研究，胸部肿瘤外科	申请考核制
2025	肿瘤学	博士	科学学位	胸部肿瘤转化研究，胸部肿瘤外科	申请考核制
2025	肿瘤外科学	硕士	专业学位	临床技能训练与研究	全国统考