Zhuang X, Lian J, Zhou Y, Cui H, Tan J, Mao W, Wang L, Wang S, Cui Y*, Zhang W*. Characterization of retrocopies in 663 individuals with esophageal squamous cell carcinoma.,iScience,2026 Mar 27;29(5):115523.

Gong W#, Yang D#, Tian J, Chai Y, Yu T, Wu Q, Wang Y, Zhang W*, Zhan Q*. Halofuginone is a Molecular Glue Degrader of Integrin β4.,Adv Sci (Weinh).,2026 May;13(30):e15970.

Cui H#, Zhu Z#, Xu E#, Qi L#, Cheng Y#, Zhang Y#, Zhang L, Cheng MY, Yang B, Sun R, Zhuang X, Xi Y, Yan T, Cheng C, Ding N, Liu H, Wang L, Guo M, Guo D, Zhang H, Peng M, An Z, Weng Y, Wang F, Liu M, Xiong R, Yin W, Song B, Zhang W*, Cheng X, Liu Z, Zhan Q*, Wang X*, Cui Y*. The consensus molecular subtypes of esophageal squamous cell carcinoma.,Signal Transduct Target Ther.,2026 Feb 19;11(1):65.

Wu Y#, Cui H#, Wang L, Ding N, Weng Y, Cheng Y, Bi S, Xiao H, Gao M, Liu H, Song Q, Zhang W*, Cui Y*. IRF2BPL transcriptionally regulates IGFBP2 to promote tumor progression and suppresses immune cell infiltration in esophageal squamous cell carcinoma.,Oncogene,2026 Feb;45(4):505-520.

Song Q, Gao M, Weng Y, Zhuang X, Wu Y, Cui H, Ding N, Wang L, Bi S, Zhang L, Zhang W*, Cui Y*. Evolutionary adaptation and asymmetric inheritance of polyploidy giant cancer cells in esophageal squamous cell carcinoma.,Cancer Letters,Volume 630, 10 October 2025, 217818

Y. Tai#, L. Kong#, Y. Wang#, D. Zhao#, X. Chen, Q. Wu, J. Hao, X. Wang, X. Liu, D. Chen, J. Li, Y. Hu, W. Zhang*, C. Yun* and Q. Zhan*, Identification and characterization of bufalin as a novel egfr degrader,Cancer Letters,623 (2025), no. 217715.

X. Liu#, M. Lv#, B. Feng#, Y. Gong, Q. Min, Y. Wang, Q. Wu, J. Chen, D. Zhao, J. Li, W. Zhang* and Q. Zhan*, Sqle amplification accelerates esophageal squamous cell carcinoma tumorigenesis and metastasis through oncometabolite 2,3-oxidosqualene repressing hippo pathway,Cancer Letters,621 (2025), no. 217528

D. Chen#, Z. Zhao#, R. Hong#, D. Yang, Y. Gong, Q. Wu, Y. Wang, Y. Cao, J. Chen, Y. Tai, H. Liu, J. Li, J. Fan, W. Zhang*, Y. Song* and Q. Zhan*, Harnessing the fgfr2/nf2/yap signaling-dependent necroptosis to develop an fgfr2/il-8 dual blockade therapeutic strategy,Nature Communications,16 (2025), no. 41281

Y. Hu#, L. Xu#, B. Feng, Q. Wu, Y. Wang, W. Gong, M. Lv, H. Zhao, J. Chen, J. Li, W. Zhang* and Q. Zhan*, Mutual regulation between cell cycle and transcription termination factor ttf2,SCI CHINA LIFE SCI,68 (2025), no. 8, 2348-2362.

18. S. Bi, Y. Wu, N. Ding, Y. Zhou, H. Liu, Y. Weng, Q. Song, L. Zhang, M. Y. Cheng, H. Cui, W. Zhang* and Y. Cui*, Three-dimensional characteristics of t cells and vasculature in the development of mouse esophageal cancer,iScience,27 (2024), no. 11138012.

D. Yeerken#, W. Xiao#, J. Li#, Y. Wang, Q. Wu, J. Chen, W. Gong, M. Lv, T. Wang, Y. Gong, R. Liu, J. Fan, J. Li, W. Zhang* and Q. Zhan*, Nlp-dependent er-to-golgi transport,INT J BIOL SCI,20 (2024), no. 8, 2881-2903.

Y. Zhou#, S. Mo#, H. Cui#, R. Sun#, W. Zhang#, X. Zhuang#, E. Xu#, H. Li, Y. Cheng, Y. Meng, M. Liu, T. Yan, H. Liu, L. Zhang, B. Yang, Y. Xi, S. Wang, X. Cheng, S. Li, Z. Liu, Q. Zhan, Z. Hu and Y. Cui, Immune-tumor interaction dictates spatially directed evolution of esophageal squamous cell carcinoma,National Science Review,11 (2024), no. nwae1505.

Zhou Y#, Mo S#, Cui H#, Sun R#, Zhang W#, Zhuang X#, Xu E, Li H, Cheng Y, Meng Y, Liu M, Yan T, Liu H, Zhang L, Yang B, Xi Y, Wang S, Cheng X, Li S, Liu Z*, Zhan Q*, Hu Z*, Cui Y*. Immune-tumor interaction dictates spatially directed evolution of esophageal squamous cell carcinoma.,National Science Review,2024 Apr 23;11(5):nwae150.

Zhuang X, Ye R, Zhou Y, Cheng MY, Cui H, Wang L, Zhang S, Wang S, Cui Y*, Zhang W*. Leveraging new methods for comprehensive characterization of mitochondrial DNA in esophageal squamous cell carcinoma.,Genome Medicine,2024 Apr 2;16(1):50.

Wang L, Zhou Y, Cui H, Zhuang X, Cheng C, Weng Y, Liu H, Wang S, Pan X*, Cui Y*, Zhang W*. IGH repertoire analysis at scale: deciphering the complexity of B cell infiltration and migration in esophageal squamous cell carcinoma.,Cancer Gene Therapy,2024 Jan;31(1):131-147.

Wang L, Zhou Y, Cui H, Zhuang X, Cheng C, Weng Y, Liu H, Wang S, Pan X*, Cui Y*, Zhang W*. IGH repertoire analysis at scale: deciphering the complexity of B cell infiltration and migration in esophageal squamous cell carcinoma.,Cancer Gene Therapy,2024 Jan;31(1):131-147.

Xuesong Liu #, Mengzhu Lv #, Weimin Zhang*, Qimin Zhan*. Dysregulation of cholesterol metabolism in cancer progression,Oncogene,42(45):3289-3302

Mengzhu Lv #, Ying Gong #, Xuesong Liu #, Yan Wang, Qingnan Wu, Jie Chen, Qingjie Min, Dongyu Zhao, Xianfeng Li, Dongshao Chen, Di Yang, Danna Yeerken, Rui Liu, Jinting Li, Weimin Zhang*, Qimin Zhan*, CDK7-YAP-LDHD axis promotes D-lactate elimination and ferroptosis defense to support cancer stem cell-like properties,Signal Transduction and Targeted Therapy,8(1):302

Ning Ding # , Yikun Cheng # , Huijuan Liu, Yueguang Wu, Yongjia Weng, Heyang Cui, Chen Cheng, Weimin Zhang*, Yongping Cui*. Fusobacterium nucleatum Infection Induces Malignant Proliferation of Esophageal Squamous Cell Carcinoma Cell by Putrescine Production.,Microbiol Spectr.,e0275922

Heyang Cui #, Yong Zhou #, Fang Wang #, Caixia Cheng #, Weimin Zhang #, Ruifang Sun #, Ling Zhang #, Yanghui Bi, Min Guo, Yan Zhou, Xinhui Wang, Jiaxin Ren, Ruibing Bai, Ning Ding, Chen Cheng, Longlong Wang, Xuehan Zhuang, Mingwei Gao, Yongjia Weng, Yueguang Wu, Huijuan Liu, Shuaicheng Li, Shubin Wang, Xiaolong Cheng, Yongping Cui*, Zhihua Liu*, Qimin Zhan*, Characterization of somatic structural variations in 528 chinese individuals with esophageal squamous cell carcinoma,Natue Communications,13(1):6296

Xuesong Liu#, Ruoxi Hong#, Peina Du#, Di Yang#, Meibo He, Qingnan Wu, Lin Li, Yan Wang, Jie Chen, Qingjie Min, Jinting Li, Weimin Zhang*, Qimin Zhan*, The metabolic genomic atlas reveals potential drivers and clinically relevant insights into the etiology of esophageal squamous cell carcinoma,THERANOSTICS,12(14):6160-6178

Chen Cheng, Heyang Cui, Huijuan Liu, Yueguang Wu, Ning Ding, Yongjia Weng, Weimin Zhang*, Yongping Cui*, Role of epidermal growth factor receptor-specific car-t cells in the suppression of esophageal squamous cell carcinoma,CANCERS,14(24):6021

Kai Zhang#, Qingnan Wu#, Wenzhong Liu, Yan Wang, Lianmei Zhao, Jie Chen, Haoyu Liu, Siqi Liu, Jinting Li, Weimin Zhang*, Qimin Zhan*, Fam135b sustains the reservoir of tip60-atm assembly to promote dna damage response,CLIN TRANSL MED,12(8):e945.

Qingnan Wu#, Weimin Zhang#, Yan Wang, Qingjie Min, Hongyue Zhang, Dezuo Dong, Qimin Zhan, Mage-c3 promotes cancer metastasis by inducing epithelial-mesenchymal transition and immunosuppression in esophageal squamous cell carcinoma,CANCER COMMUN,41(12):1354-1372

肿瘤微环境可塑性

常山酮衍生物及其药物组合物和用途, 发明专利, 第3完成人, 北京肿瘤医院, 中国, 2021.12

一种经修饰的免疫细胞或其前体细胞, 发明专利, 第3完成人, 深圳湾实验室, 中国, 2025.6

D-乳酸在制备治疗和/或预防食管鳞状细胞癌药物中的用途, 发明专利, 第3完成人, 北京大学肿瘤医院, 中国, 2024.2

LDHD 抑制剂及其在制备治疗和/或预防食管鳞状细胞癌药物中的用途, 发明专利, 第3完成人, 北京大学肿瘤医院, 中国, 2024.4

基因PTHLH作为靶点在食管鳞癌辅助诊断、预后判断和治疗中的应用, 发明专利, 第4完成人, 深圳北京大学香港科技大学医学中心, 中国, 2026.2

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DH3β与中心体蛋白相互作用的分子机理及其作为肿瘤潜在治疗靶点的研究, 课题负责人, 2019.11.1～2023.8.1, 北京市科技新星项目

中国高发恶性肿瘤免疫生态演进机制及免疫诊疗新技术研发-课题一：中国高发恶性肿瘤抗原鉴定新技术及功能性图谱绘制, 课题负责人, 2024.8.1～2028.7.31, 科技创新2030-癌症、心脑血管、呼吸和代谢性疾病防治研究国家科技重大专项

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mTOR/FAM135B/ATG16L1信号通路抑制自噬发生在食管鳞癌发生发展中的作用及机制研究, 课题负责人, 2019.1.1～2021.12.31, 国家自然基金

基于核酸适体技术的三阴性乳腺癌细胞表面多组学精准诊疗体系研究, 参加者, 2026.1.1～2029.12.31, 国自然联合基金重大项目

Nlp调控COPII囊泡转运的机制及其在肿瘤发生发展中的作用, 课题负责人, 2022.1.1～2025.12.31, 国家自然基金面上项目

联合靶向天冬氨酸代谢和免疫检查点提高乳腺癌治疗疗效的机制研究, 课题负责人, 2019.9.1～2021.12.31, 北京市医管中心“青苗计划”