导师基本信息
- 姓名：杨芬
- 性别：女
- 民族：汉族
- 科室：临床药理基地
- 职称：副研究员
- 专业：肿瘤学
- E-MAIL： yangfen_bj@bjmu.edu.cn
学术论文 | 研究方向 | 科研项目 | 招生计划
Xiaoqing Li #, Yunhai Bo #, Le Le 1, Fen Yang*.Simultaneous Determination of D and L Enantiomers of 2-Hydroxyglutarate by UHPLC-MS/MS Method in Human Biological Fluids and its Clinical Application,J Chromatogr Sci.,2024, 00, 1–9
Xiaoqing Li#, Yunhai Bo , Qingping Zeng , Lei Diao , Stephanie Greene , John Patterson, Lu Liu, Fen Yang* Population pharmacokinetic model for oral ORIN1001 in Chinese patients with advanced solid tumors.,Frontiers in pharmacology,2024:15:1322557
Xiaoqing Li #, Yunhai Bo #, Han Yin, Xiaohong Liu, Xu Li and Fen Yang *. Population pharmacokinetic analysis of TQ-B3203 following intravenous administration of TQ-B3203 liposome injection in Chinese patients with advanced solid tumors.,Frontiers in pharmacology,2023,14:1102244
Xian Ding#, Fen Yang#, Yanhua Chen*, Jing Xu, Jiuming He, Ruiping Zhang, Zeper Abliz * Norm ISWSVR: A Data Integration and Normalization Approach for Large-Scale Metabolomics,Analytical Chemistry,2022,94(21):7500-7509
Fen Yang#,*, Huali Wu#, Yunhai Bo , Ye Lu, Hong Pan, Su Li, Qin Lu, Simin Xie, Harry Liao, Bing Wang. Population Pharmacokinetic Modeling and Simulation of TQ-B3101 To Inform Dosing in Pediatric Patients with Solid Tumors,Frontiers in pharmacology,2022,12:782518
Fen Yang#, Jun Zhou#, Yun hai Bo, Han Yin, Xiaohong Liu, Jian Li? A validated UHPLC-MS/MS method for determination of TQ-B3203 in human plasma and its application to a pharmacokinetic study in Chinese patients with advanced solid tumor.,J Sep Sci.,2021; 44: 945-953
Jun Zhou #, Fen Yang#, Jia jia Yuan , Yun hai Bo, Ji fang Gong, Lin Shen*.Determination of a novel photosensitizer sinoporphyrin sodium in human plasma by ultra- performance liquid chromatography-tandem mass spectrometry.,Journal of Pharmaceutical and Biomedical Analysis,2021, 195, 113852
Fen Yang#, Ji fang Gong, #*, Lin Shen, Chen Zhang, Fu rong Kou, Jing Gao, Yan Li, Guo bing Xu. Development of an LC-MS/MS method for quantitative analysis of Chlorogenic acid in human plasma and its application to a pharmacokinetic study in Chinese patients with advanced solid tumor.,Journal of Pharmaceutical and Biomedical Analysis,2020, 177, 5 January, 112809
基于药物代谢组学和药物基因遗传学的伊立替康毒性及作用机制研究, 课题负责人, 2021.1.1～2024.12.31, 国家自然科学基金委员会
首创 1 类新药注射用绿原酸的Ⅰ/Ⅱ期临床研究, 参加者, 2016.1.1～2019.12.31, 科技部重大专项
基于拟靶向代谢组学的胃癌化疗敏感性预测模型的研究, 课题负责人, 2017.1.1～2019.12.31, 国家自然科学基金委员会
社会任职
- 北京市科学技术委员会、中关村科技园区管理委员会科技项目评审专家
- 国家自然科学基金评审专家
- 中国临床药理学杂志青年委员
- 北京肿瘤医院伦理委员
- 国家药品监督管理局食品药品审核查验中心评审员
学习、工作经历
- 2018.1.1～，北京肿瘤医院国家药物临床试验机构，I期临床实验室，副研究员，副主任
- 2013.4.1～2017.12.31，北京肿瘤医院国家药物临床试验机构，I期临床实验室，助理研究员
- 2009.9.1～2013.3.31，北京协和医院，临床药理中心，博士后
- 2007.7.1～2009.8.31，中国科学院植物研究所，助理研究员
- 2004.9.1～2007.7.1，中国医学科学院，中国协和医科大学，药物研究所，博士
