Xiaoqing Li #, Yunhai Bo #, Le Le 1, Fen Yang*.Simultaneous Determination of D and L Enantiomers of 2-Hydroxyglutarate by UHPLC-MS/MS Method in Human Biological Fluids and its Clinical Application,J Chromatogr Sci.,2024, 00, 1–9

Xiaoqing Li#, Yunhai Bo , Qingping Zeng , Lei Diao , Stephanie Greene , John Patterson, Lu Liu, Fen Yang* Population pharmacokinetic model for oral ORIN1001 in Chinese patients with advanced solid tumors.,Frontiers in pharmacology,2024:15:1322557

Xiaoqing Li #, Yunhai Bo #, Han Yin, Xiaohong Liu, Xu Li and Fen Yang *. Population pharmacokinetic analysis of TQ-B3203 following intravenous administration of TQ-B3203 liposome injection in Chinese patients with advanced solid tumors.,Frontiers in pharmacology,2023,14:1102244

Xian Ding#, Fen Yang#, Yanhua Chen*, Jing Xu, Jiuming He, Ruiping Zhang, Zeper Abliz * Norm ISWSVR: A Data Integration and Normalization Approach for Large-Scale Metabolomics,Analytical Chemistry,2022,94(21):7500-7509

Fen Yang#,*, Huali Wu#, Yunhai Bo , Ye Lu, Hong Pan, Su Li, Qin Lu, Simin Xie, Harry Liao, Bing Wang. Population Pharmacokinetic Modeling and Simulation of TQ-B3101 To Inform Dosing in Pediatric Patients with Solid Tumors,Frontiers in pharmacology,2022,12:782518

Fen Yang#, Jun Zhou#, Yun hai Bo, Han Yin, Xiaohong Liu, Jian Li? A validated UHPLC-MS/MS method for determination of TQ-B3203 in human plasma and its application to a pharmacokinetic study in Chinese patients with advanced solid tumor.,J Sep Sci.,2021; 44: 945-953

Jun Zhou #, Fen Yang#, Jia jia Yuan , Yun hai Bo, Ji fang Gong, Lin Shen*.Determination of a novel photosensitizer sinoporphyrin sodium in human plasma by ultra- performance liquid chromatography-tandem mass spectrometry.,Journal of Pharmaceutical and Biomedical Analysis,2021, 195, 113852

抗肿瘤新药的早期临床研究和转化研究

基于药物代谢组学和基因组学的抗肿瘤药物耐药机制研究

基于药物代谢组学和药物基因遗传学的伊立替康毒性及作用机制研究, 课题负责人, 2021.1.1～2024.12.31, 国家自然科学基金委员会