Xu T#, Dai J#, Tang L, Sun L, Si L, Guo J. Systemic administration of STING agonist promotes myeloid cells maturation and antitumor immunity through regulating hematopoietic stem and progenitor cell fate.,Cancer Immunology, Immunotherapy,2023 Aug 7. doi: 10.1007/s00262-023-03502-7. Epub ahead of print. PMID: 37550427.

Dai J, Bai X, Gao X, et al. Molecular underpinnings of exceptional response in primary malignant melanoma of the esophagus to anti-PD-1 monotherapy.,J Immunother Cancer,11(1):e005937

Dai J, Yang L, Guo J. Response to: Polymorphism within the 3'-untranslated region of denticleless E3 ubiquitin protein ligase homolog and survival in acral melanoma.,European Journal of Cancer,124:65-66

Yang L#, Dai J#, Ma M, Mao L, Si L, Cui C, Sheng X, Chi Z, Yu S, Xu T, Yu J, Kong Y*, Guo J*. Identification of a functional polymorphism within the 3'-untranslated region of denticleless E3 ubiquitin protein ligase homolog associated with survival in acral melanoma.,European Journal of Cancer,118:70-81

Ma M#, Dai J#, Tang H, Xu T, Yu S, Si L, Cui C, Sheng X, Chi Z, Mao L, Wu X, Yang L, Yu H, Li S, Lian B, Tang B, Wang X, Yan X, Bai X, Zhou L, Kong Y*, Guo J*. microRNA-23a-3p inhibits mucosal melanoma mrowth and progression through targeting adenylate cyclase 1 and attenuating cAMP and MAPK pathways.,Theranostics,9(4):945-960

Mao L#, Dai J#, Cao Y#, Bai X, Sheng X, Chi Z, Cui C, Kong Y, Zhang Y, Wu L, Wang X, Tang B, Lian B, Yan X, Li S, Zhou L, Wei X, Li C, Qi Z, Si L, Guo J. Palbociclib in advanced acral melanoma with genetic aberrations in the cyclin-dependent kinase 4 pathway.,Eur J Cancer,2021 May;148:297-306.

Bai X#, Dai J#, Li C, Cui C, Mao L, Wei X, Sheng X, Chi Z, Yan X, Tang B, Lian B, Wang X, Zhou L, Li S, Kong Y, Qi Z, Xu H, Duan R, Guo J, Si L. Risk models for advanced melanoma patients under anti-PD-1 monotherapy-ad hoc?analyses of pooled data from two clinical trials.,Front Oncol,2021 May 20;11:639085.

Xu T#, Dai J#, Tang L, Yang L, Si L, Sheng X, Cui C, Chi Z, Kong Y, Guo J. EZH2 inhibitor enhances the STING agonist?induced antitumor immunity in melanoma.,J Invest Dermatol,2022;142(4):1158-1170.

肿瘤分子标志物和肿瘤免疫

STING通路调控造血干细胞髓系定向分化及诱导训练免疫的机制研究, 课题负责人, 2024.1.1～2027.12.31, 国家自然科学基金面上项目

KIT基因变异调控黑色素瘤免疫微环境的分子机制及治疗策略研究, 课题负责人, 2021.1.1～2024.12.31, 国家自然科学基金面上项目

外泌体介导的免疫相关膜蛋白在粘膜型黑色素瘤中的功能分析及临床应用价值研究, 课题负责人, 2020.1.1～2022.12.31, 北京市自然科学基金面上项目

小RNA与粘膜型黑色素瘤转移, 课题负责人, 2017.1.1～2019.12.31, 北京市优秀人才培养资助青年拔尖个人项目

新型STING激动剂抗黑色素瘤的作用机制, 课题负责人, 2023.1.1～2024.12.31, 北京市医院管理中心“青苗”人才

研究生招生计划

招生年度	招生专业	学位级别	学位类型	研究方向	选拔方式	操作
2024	肿瘤学	硕士	科学学位	肿瘤分子标志物和肿瘤免疫	全国统考