Zhichao Tan#,Yan Wu#,Zhengfu Fan,Tian Gao,Sijuan Ding,Liang Han,Suxia Luo,Qingxia Fan,Jianhua Shi,Chujie Bai,Ruifeng Xue,Shu Li,Lu Zhang,Xinyu Wang,Ling Jia,Lixin Zhou,Binlei Liu,Jing Huang,Jiayong Liu*. Intratumoral oncolytic virus OH2 injection in patients with locally advanced or metastatic sarcoma: a phase 1/2 trial.,Journal of Immunotherapy of Cancer.,2025, Jan 16, 13(1):e010543.

Zhichao Tan#, Yan Wu#, Zhengfu Fan#,Tian Gao, Wei Guo, Chujie Bai, Ruifeng Xue, Shu Li, Lu Zhang, Xinyu Wang, Ling Jia, Jiayong Liu*. Anlotinib plus TQB2450, a PD-L1 Antibody, in Patients with Advanced Alveolar Soft Part Sarcoma: A Single-Arm, Phase II Trial.,Clinical Cancer Research,2024. Sep 16;30(24):5577-5583.

Jiayong Liu#,Xuan Wang#,Zhongwu Li#,Shunyu Gao#,Lili Mao,Jie Dai,Caili Li,Chuanliang Cui,Zhihong Chi,Xinan Sheng,Yumei Lai,Zhichao Tan,Bin Lian,Bixia Tang,Xieqiao Yan,Siming Li,Li Zhou,?Xiaoting Wei,Juan Li,Jun Guo,Lu Si*. Neoadjuvant oncolytic virus orienx010 and toripalimab in resectable acral melanoma: a phase Ib trial.,Signal Transduction and Targeted Therapy,2024, Nov 22; 9(1):318.

Qiuzhong Pan?#,?Desheng Weng?#,?Jiayong Liu?#,?Zhaosheng Han?#,?Yusheng Ou,?Bushu Xu,?Ruiqing Peng,?Yi Que,?Xizhi Wen,?Jing Yang,?Shi Zhong,?Lun Zeng,?Aiyuan Chen,?Haiping Gong,?Yanmei Lin,?Jiewen Chen,?Ke Ma,?Johnson Y N Lau,?Yi Li,?Zhengfu Fan*,?Xing Zhang*. Phase 1 clinical trial to assess safety and efficacy of NY-ESO-1-specific TCR T cells in HLA-A?02:01 patients with advanced soft tissue sarcoma.,Cell Reports. Medicine,2023, Aug 15; 4(8):101133

Jiayong Liu*, Tian Gao*, Zhichao Tan*, Shu Li, Jie Xu, Chujie Bai, Ruifeng Xue, Lu Xie, Lu Zhang, Zhengfu Fan#, Wei Guo#. Phase II Study of TQB2450, a Novel PD-L1 Antibody, in Combination with Anlotinib in Patients with Locally Advanced or Metastatic Soft Tissue Sarcoma.,Clinical Cancer Research.,2022. 28(16):3473-3479

Chaohu Pan*, Qiaomei Cai*, Xiaorong Li, Lili Li, Liping Yang, Yu Chen, Junxiao Liu, Wancheng Liu, Meiling Gao, Tianqi Sui, Xiaoyang Wang, Huiming Fan, Jiayin Ruan, Yueyue Shi, Saihua Chen, Lucy S Cheng, Jiayong Liu #, Heng Yang #, Genhong Cheng#. Enhancing the HSV-1-mediated antitumor immune response by suppressing Bach1.,Cellular & Molecular Immunology,2022. 19(4):516-526

Zhichao Tan*, Jiayong Liu*#, Ruifeng Xue?, Zhengfu Fan, Chujie Bai, Shu Li, Tian Gao, Lu Zhang and Xinyu Wang. Clinical features and therapeutic outcomes of alveolar soft part sarcoma in children: A single-center, retrospective study.,Frontiers in Oncology,12:1019911. doi: 10.3389/fonc.2022.1019911.

Yuxing Huang*, Jing Su*, Jiayong Liu*, Xin Yi, Fang Zhou, Jiaran Zhang, Jiaxiang Wang, Xuan Meng, Lu Si #, Congying Wu #. YAP Activation in Promoting Negative Durotaxis and Acral Melanoma Progression.,Cells,2022. 11(22):3543. doi: 10.3390/cells11223543.

Jiayong Liu* #, Peijie Liu, Fuyu Gong, Youhui Tian, Xiaochen Zhao. Case Report: A PD-L1-Positive Patient With Pleomorphic Rhabdomyosarcoma Achieving an Impressive Response to Immunotherapy.,Frontiers in Immunology.,2022. 17;13:815598

Zhichao Tan, Xinyu Wang#, Jiayong Liu# *, Zhengfu Fan, Tian Gao, Chujie Bai, Ruifeng Xue, Shu Li, Lu Zhang. Efficacy of PD-1 inhibitors combined with pegylated liposomal doxorubicin and dacarbazine compared with liposomal doxorubicin and dacarbazine in advanced leiomyosarcoma patients：a retrospective, single-institutional cohort study.,Annals of Translational Medicine.,2022,10(18):1000.

Jiayong Liu* #, Zhichao Tan*, Ruifeng Xue*, Zhengfu Fan, Chujie Bai, Shu Li, Tian Gao, Lu Zhang, Zhiwei Fang, Lu Si #. The efficacy of Tc-99m- rituximab as a tracer for sentinel lymph node biopsy in cutaneous melanoma patients.,Annals of Translational Medicine,2022. 10(2):95. doi: 10.21037/atm-21-6890.

Jiayong Liu* #, Zhengfu Fan, Chujie Bai, Shu Li, Ruifeng Xue, Tian Gao, Lu Zhang, Zhichao Tan, Zhiwei Fang. Real-world experience with pembrolizumab in patients with advanced soft tissue sarcoma.,Annals of Translational Medicine,2021. 9(4):339. doi: 10.21037/atm-21-49.

Jiayong Liu*, Zhengfu Fan*, Marc El Beaino, Valerae O Lewis, Bryan S Moon, Robert L Satcher, Justin E Bird, Spencer J Frink, Patrick P Lin #. Surgical drainage after limb salvage surgery and endoprosthetic reconstruction: is 30 mL/day critical?,Journal of Orthopaedic Surgery and Research,2021. 15;16(1):137. doi: 10.1186/s13018-021-02276-x.

Jiayong Liu* #, Zhengfu Fan, Shu Li, Tian Gao, Ruifeng Xue, Chujie Bai, Lu Zhang, Zhichao Tan, Zhiwei Fang. Target therapy for metastatic alveolar soft part sarcoma: a retrospective study with 47 cases.,Annals of Translational Medicine,2020. 8(22):1493. doi: 10.21037/atm-20-6377.

Jia-Yong Liu* #, Bao-Rang Zhu, Yu-Dong Wang, Xin Sun. The efficacy and safety of apatinib mesylate in the treatment of metastatic osteosarcoma patients who progressed after standard therapy and the VEGFR2 gene polymorphism analysis.,International Journal of Clinical Oncology.,2020. 25(6):1195-1205. doi: 10.1007/s10147-020-01644-7.

原发性心脏肉瘤：化疗联合免疫治疗的疗效探索及通过多组学方法对患者预后的进行预测价值, 课题负责人, 2025.1.1～2027.12.31, 北京市属医院 科研培育计划项目

软组织肉瘤：新辅助大分割放疗联合化疗的治疗可行性及多组学结合的人工智能疗效预测模型构建, 课题负责人, 2025.1.1～2027.12.31, 北京大学世纪金源“腾云临床研究专项”

作为PI主持多项注册类及IIT临床研究，其中目前仍在研的项目包括： 注册类试验：1、AN4005治疗晚期肿瘤患者的开放、多中心、I期研究；2、一项评估DB-1311在晚期/转移性实体瘤受试者中的安全性、耐受性、药代动力学和初步抗肿瘤活性的I/IIa期、多中心、开放性、首次人体研究 IIT项目：1、评估IBI363治疗晚期转移或不可切除软组织肉瘤（Ⅳ期）受试者的安全性、耐受性和有效性的Ⅰ期临床研究；2、评估【225Ac】Ac-FAPI-XT注射液在FAP表达阳性的晚期实体瘤患者中安全性、耐受性、辐射剂量学特征以及初步有效性的临床研究；3、脂质体多柔比星+达卡巴嗪联合特瑞普利单抗治疗不可切除或转移性心脏肉瘤的研究；, 课题负责人, 2024.1.10～2026.12.31, 临床试验

TFE3基因对肿瘤细胞免疫原性的影响, 课题负责人, 2021.1.1～2024.12.31, 吴阶平医学基金会 临床科研专项资助基金

研究生招生计划

招生年度	招生专业	学位级别	学位类型	研究方向	选拔方式	操作
2025	肿瘤外科学	硕士	专业学位	临床技能训练与研究	全国统考