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导师基本信息

  • 姓名:邢蕊
  • 性别:
  • 民族:汉族
  • 科室:胃肠肿瘤生物学研究室
  • 职称:研究员 ,副教授
  • 专业:医学生物化学与分子生物学
  • E-MAIL: sherry19820420@hotmail.com

学术论文 | 研究方向 | 科研项目

Rui Xing#,*, Yong Zhou*, Jun Yu*, Yingyan Yu*, Yongzhan Nie*, Wen Luo*, Chao Yang*, Teng Xiong,WILLIAM k.k. Wu, Zhongwu Li, Yang Bin, Shunye Lin, Yingqi Hu,Lin Li, Lijuan Han, Chen Yang, Shaogang Huang,Suiping Huang, Rui Zhou, Jing Li, Kaichun Wu, Daiming Fan, Guangbo Tang, Jianhua Dou, Zhenggang Zhu,Jiafu Ji#, Xiaodong Fang#, Youyong Lu#. Whole-genome sequencing reveals novel rndem-duplication hospots and a prognosic mutational signature in gasric cancer.,Nature communications,(2019) 10:2037

Yang B#, Wu A#, Hu Y, Cui Tao, Wang JM, Lu Y and Xing R: Mucin 17 inhibits the progression of human gastric cancer by limiting inflammatory responses through a MYH9-p53-RhoA regulatory feedback loop,Journal of Experimental & Clinical Cancer Research,38(1):283

Peng L#, Xing R#, Liu D#, Bao L#, Cheng W, Wang H, Yu Y, Liu X, Jiang L, Wu Y, An Z, Liang Q, Kim RN, Shin YKe, Yang H, Wang J, Yu J, Zhang X, Xu X, Yang J, Wu K, Zhu S* and Lu Y*: Characterization and validation of somatic mutation spectrum to reveal heterogeneity in gastric cancer by single cell sequencing,Science Bulletin,64:236-244

Yan J, Yang B, Lin S, Xing R* and Lu Y*: Downregulation of miR-142-5p promotes tumor metastasis through directly regulating CYR61 expression in gastric cancer,Gastric cancer,22(2): 302-313

Xia N, Cui J, Zhu M, Xing R* and Lu Y*: Androgen receptor variant 12 promotes migration and invasion by regulating MYLK in gastric cancer,Journal of pathology,248(3):304-315.

Zhu M#, Wang H#, Cui J, Li W, Pan Y, An G, Zhang Q*, Xing R*, Lu Y*: Calcium-binding protein S100A14 induces differentiation and suppresses metastasis in gastric cancer,Cell death and disease,

Lin S, Zhang Y, Hu Y, Yang B, Cui J, Huang J, Wang JM, Xing R* and Lu Y*: Epigenetic downregulation of MUC17 by H. pylori infection facilitates NF-κB-mediated expression of CEACAM1-3S in human gastric cancer,Gastric cancer,

Zhu H#, Zhang L#, Yan S, Li W, Cui J, Xia N, Yang Y, Yuan J, Chen X, Luo J, Chen R*, Xing R*, Lu Y*, Wu N*: LncRNA16 is a potential biomarker for diagnosis of early-stage lung cancer that promotes cell proliferation by regulating the cell cycle,Oncotarget,8(5):7867-77

早期胃癌中ZFP36L2的拷贝数扩增及其诱导染色体不稳定的分子机制, 课题负责人 , 2018.1.1~2021.12.12, 国家自然科学基金面上项目、81772502

MUC17抵御幽门螺杆菌的作用机制及其临床应用, 课题负责人 , 2018.1.1~2020.12.1, 北京市自然科学基金面上项目、7182027

胃癌靶向治疗新技术研究, 子课题负责人 , 2017.7.11~2020.12.11, 科技部、2017YFC1308900

基于多组学的消化道癌分子分型研究项目, 子课题负责人 , 2018.1.1~2020.12.31, 1-2-2-36

北京市青年拔尖人才项目, 课题负责人 , 2017.1.8~2019.12.31, 北京市青年拔尖人才项目

胃癌组织中Mucin17的基因突变及其抗炎作用的分子调控机制, 课题负责人 , 2016.1.1~2019.12.31, 国家自然科学基金面上项目、81572346

北京市科技新星, 课题负责人 , 2015.1.1~2017.12.31, 北京市科技新星

学习、工作经历

  • 2021.6.1~,北京市肿瘤防治研究所 博士生导师
  • 2021.3.1~,北京市肿瘤防治研究所 研究员
  • 2016.8.1~,北京市肿瘤防治研究所 PI
  • 2015.8.1~2021.3.1,北京市肿瘤防治研究所 副教授/副研究员
  • 2010.8.1~2015.8.1,北京市肿瘤防治研究所 助理研究员