导师基本信息
- 姓名：韩淑燕
- 性别：女
- 民族：汉族
- 科室：中西医结合科暨老年肿瘤科
- 职称：研究员,教授
- 专业：中西医结合基础、肿瘤学
- E-MAIL： shuyanhan@bjmu.edu.cn
学术论文 | 综述述评 | 研究方向 | 科研项目
Guo Y, Deng X, Wang S, Yuan Y, Guo Z, Hao H, Jiao Y, Li P, Han S. SILAC proteomics based on 3D cell spheroids unveils the role of RAC2 in regulating the crosstalk between triple-negative breast cancer cells and tumor-associated macrophages,Int J Biol Macromol,Int J Biol Macromol. 2024 Jan;254(Pt 1):127639. doi: 10.1016/j.ijbiomac.2023.127639. Epub 2023 Oct 23.
Han S, Tian Z, Tian H, Han H, Zhao J, Jiao Y, Wang C, Hao H, Wang S, Fu J, Xue D, Sun H, Li P. HDGF promotes gefitinib resistance by activating the PI3K/AKT and MEK/ERK signaling pathways in non-small cell lung cancer,Cell Death Discov,Cell Death Discov. 2023 Jun 10;9(1):181. doi: 10.1038/s41420-023-01476-0.
Yuan Y, Guo Y, Guo ZW, Hao HF, Jiao YN, Deng XX, Han SY. Marsdenia tenacissima extract induces endoplasmic reticulum stress-associated immunogenic cell death in non-small cell lung cancer cells through targeting AXL,J Ethnopharmacol,J Ethnopharmacol. 2023 Oct 5;314:116620. doi: 10.1016/j.jep.2023.116620. Epub 2023 May 18.
Guo Z, Wang S, Hao H, Deng X, Fu J, Guo Y, Yuan Y, Jiao Y, Han S. Targeting Ferroptosis in Cancer by Natural Products: An Updated Review,Am J Chin Med,Am J Chin Med. 2023;51(3):547-574. doi: 10.1142/S0192415X23500271. Epub 2023 May 17.
Han S, Hao H, Han H, Xue D, Jiao Y, Xie Y, Xu Y, Huangfu L, Fu J, Wang S, Sun H, Li P, Zhou Q. CUEDC2 Drives β-Catenin Nuclear Translocation and Promotes Triple-Negative Breast Cancer Tumorigenesis,Cells,Cells. 2022 Sep 29;11(19):3067. doi: 10.3390/cells11193067.
Wang S, Hao HF, Jiao YN, Fu JL, Guo ZW, Guo Y, Yuan Y, Li PP, Han SY. Dandelion extract inhibits triple-negative breast cancer cell proliferation by interfering with glycerophospholipids and unsaturated fatty acids metabolism,Front Pharmacol,Front Pharmacol. 2022 Sep 6;13:942996. doi: 10.3389/fphar.2022.942996. eCollection 2022.
Hao H, Guo Z, Li Z, Li J, Jiang S, Fu J, Jiao Y, Deng X, Han S, Li P. Modified Bu-Fei decoction inhibits lung metastasis via suppressing angiopoietin-like 4,Phytomedicine,Phytomedicine. 2022 Nov;106:154409. doi: 10.1016/j.phymed.2022.154409. Epub 2022 Aug 28.
Fu JL, Hao HF, Wang S, Jiao YN, Li PP, Han SY. Marsdenia tenacissima extract disturbs the interaction between tumor-associated macrophages and non-small cell lung cancer cells by targeting HDGF,J Ethnopharmacol,J Ethnopharmacol. 2022 Nov 15;298:115607. doi: 10.1016/j.jep.2022.115607. Epub 2022 Aug 13.
Wang S, Fu JL, Hao HF, Jiao YN, Li PP, Han SY. Metabolic reprogramming by traditional Chinese medicine and its role in effective cancer therapy,Pharmacol Res,Pharmacol Res. 2021 Aug;170:105728. doi: 10.1016/j.phrs.2021.105728. Epub 2021 Jun 11.
Deng XX, Jiao YN , Hao HF, Xue D*, Bai CC*, Han SY*. Taraxacum mongolicum extract inhibited malignant phenotype of triple-negative breast cancer cells in tumor-associated macrophages microenvironment through suppressing IL-10 / STAT3 / PD-L1.,J Ethnopharmacol.,2021, 274:113978.
Zhao C#, Hao HF#, Zhao HY, Ren W, An G, Sun H, Han SY*, Li PP*. Marsdenia tenacissima extract promotes gefitinib accumulation in tumor tissues of non-small cell lung cancer (NSCLC) xenograft mice.,J Ethnopharmacol.,2020, 255: 112770
Zhang JX, Yuan WC, Li CG, Zhang HY, Han SY, Li XH. A review on the mechanisms underlying the antitumor effects of natural products by targeting the endoplasmic reticulum stress apoptosis pathway,Front Pharmacol,Front Pharmacol. 2023 Nov 17;14:1293130. doi: 10.3389/fphar.2023.1293130. eCollection 2023.
Wang S, Fu JL, Hao HF, Jiao YN, Li PP*, Han SY*,Pharmacol Res,170:105728
Deng XX, Zhao SP, Liu XQ, Han L, Wang RZ, Hao HF, Jiao YN, Han SY*, Bai CC*. Polygala tenuifolia: a source for anti-Alzheimer’s disease drugs.,Pharm Biol.,2020, 58(1): 410-416.
CUEDC2/TLR2反馈回路介导蒲公英提取物调控三阴乳腺癌肿瘤干细胞和巨噬细胞的串扰, 课题负责人, 2024.1.1～2027.12.31, 国家自然科学基金面上项目
蒲公英通过CUEDC2调节肿瘤细胞与TAMs的交互作用重塑三阴乳腺癌免疫微环境, 课题负责人, 2021.1.1～2024.12.31, 国家自然科学基金面上项目
蒲公英提取物通过CUEDC2影响三阴乳腺癌干细胞干性抑制其恶性表型的分子机制, 课题负责人, 2019.1.1～2022.12.31, 国家自然科学基金面上项目
