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导师基本信息

  • 姓名:苏向前
  • 性别:
  • 民族:满族
  • 科室:胃肠肿瘤中心四病区
  • 职称:主任医师 ,教授
  • 专业:肿瘤学 ,肿瘤外科学
  • E-MAIL: suxiangqian@gmail.com

学术论文 | 研究方向 | 科研项目

KIF14 promotes cell proliferation via activation of Akt and is directly targeted by miR-200c in colorectal cancer.,Int J Oncol.,

Clonality and heterogeneity of metachronous colorectal cancer,Mol Carcinog,

Short-term surgical outcomes of laparoscopy-assisted versus open D2 distal gastrectomy for locally advanced gastric cancer in North China: a multicenter randomized controlled trial. Surg Endosc.,Surg Endosc,

Di J, Yang H, Jiang B, Su X(苏向前)*. Whole exome sequencing reveals intertumor heterogeneity and distinct genetic origins of sporadic synchronous colorectal cancer. Int J Cancer.,Int J Cancer.,

1. Yu J, Huang C, Sun Y, Su X(苏向前), Cao H, Hu J, Wang K, Suo J, Tao K, He X, Wei H, Ying M, Hu W, Du X, Hu Y, Liu H, Zheng C, Li P, Xie J, Liu F, Li Z, Zhao G, Yang K, Liu C, Li H, Chen P, Ji J, Li G; Chinese Laparoscopic Gastrointestinal Surgery Study (CLASS) Group. Effect of Laparoscopic vs Open Distal Gastrectomy on 3-Year Disease-Free Survival in Patients With Locally Advanced Gastric Cancer: The CLASS-01 Randomized Clinical Trial,JAMA,

Wang Z, Yang J, Di J, Cui M, Xing J, Wu F, Wu W, Yang H, Zhang C, Yao Z, Zhang N, Jiang B*, Su X(苏向前)*. Downregulated USP3 mRNA functions as a competitive endogenous RNA of SMAD4 by sponging miR-224 and promotes metastasis in colorectal cancer. ,Sci Rep ,7(1):4281.

Zhuang M, Peng Z, Wang J, Su X(苏向前)*. Vascular endothelial growth factor gene polymorphisms and gastric cancer risk: a meta-analysis. ,J BUON ,22(3):714-724.

Wu W, Wu F, Wang Z, Di J, Yang J, Gao P, Jiang B*, Su X(苏向前)*. CENPH inhibits rapamycin sensitivity by regulating GOLPH3-dependent mTOR signaling pathway in colorectal cancer. ,J Cancer ,8: 2163-2172.

Wang A, Cui M, Qu H, Di J, Wang Z, Xing J, Wu F, Wu W, Wang X, Shen L, Jiang B*, Su X(苏向前)*. Induction of anti-EGFR immune response with mimotopes identified from a phage display peptide library by panitumumab. ,Oncotarget ,7(46):75293-75306

Xu K, Wang J, Gao J, Di J, Jiang B, Chen L, Wang Z, Wang A, Wu F, Wu W, Shen L, Su X(苏向前)*. GATA binding protein 2 overexpression is associated with poor prognosis in KRAS mutant colorectal cancer. ,Oncol Rep ,36(3):1672-8.

Hu Y#, Huang C#, Sun Y#, Su X(苏向前)#, Cao H, Hu J, Xue Y, Suo J, Tao K, He X, Wei H, Ying M, Hu W, Du X, Chen P, Liu H, Zheng C, Liu F, Yu J, Li Z, Zhao G, Chen X, Wang K, Li P, Xing J, Li G. ,J Clin Oncol ,34(12):1350-7.

Zhang C, Di J, Jiang B, Cui M, Wang Z, Xing J, Yang H, Yao Z, Zhang N, Su X(苏向前)*. Prognostic factors for patients with stage II colon cancer: results of a prospective study. ,Int J Colorectal Dis ,31(1):123-9.

Cui M, Gong C, Jiang B, Yao Z, Chen L, Di J, Xing J, Yang H, Zhang C, Zhang N, Liu M, Tan F, Wang Z, Su X(苏向前)*. Evaluation of immune responses of gastric cancer patients treated by laparoscopic and open gastrectomy. ,Med Oncol ,32(11):253.

Cui M, Li Z, Xing J, Yao Z, Liu M, Chen L, Zhang C, Yang H, Zhang N, Tan F, Jiang B, Di J, Wang Z, Ji J, Su X(苏向前)*. A prospective randomized clinical trial comparing D2 dissection in laparoscopic and open gastrectomy for gastric cancer. ,Med Oncol ,32(10):241.

Liu X, Jiang B, Wang A, Di J, Wang Z, Chen L, Su X(苏向前)*. GATA2 rs2335052 Polymorphism Predicts the Survival of Patients with Colorectal Cancer. ,PLoS One ,10(8):e0136020.

Mingshan Liu, Jiabo Di, Yang Liu, Zhe Su, Beihai Jiang, Zaozao Wang, Xiangqian Su(苏向前)*. Comparison of EpCAM high CD44+ cancer stem cells with EpCAM high CD44- tumor cells in colon cancer by single-cell sequencing. ,Cancer Biol Ther ,1-9

Di J, Yang H, Jiang B, Wang Z, Ji J, Su X(苏向前)*. Whole exome sequencing reveals intertumor heterogeneity and distinct genetic origins of sporadic synchronous colorectal cancer. ,Int J Cancer ,142(5):927-939.

Di J, Zhuang M, Yang H, Jiang B, Wang Z, Su X(苏向前)*. Clinical significance of circulating immune cells in left- and right-sided colon cancer. ,PeerJ ,5:e4153.

Liu M, Liu Y, Di J, Su Z, Yang H, Jiang B, Wang Z, Zhuang M, Bai F*, Su X(苏向前)*. Multi-region and single-cell sequencing reveal variable genomic heterogeneity in rectal cancer. ,BMC Cancer ,17(1):787.

ENST00000428100通过MACC1调节mTOR通路影响结肠癌干细胞代谢可塑性的机制研究 , 课题负责人 , 2017.1.1~2020.12.31, 国家自然科学基金面上项目(81672439)

SOK1通过mTOR通路调节结肠癌Warburg效应的分子机制研究 , 课题负责人 , 2016.1.1~2018.12.31, 北京市自然科学基金面上项目(7162039)

利用单细胞基因组测序技术探寻结直肠癌干细胞的异质性及其分子机制 , 课题负责人 , 2014.9.1~2017.9.30, 北京大学“985工程”三期临床医院合作专项/2014-5-1

社会任职

  • 美国胃肠与内镜外科医师协会会员(SAGES)
  • 欧洲内视镜外科协会会员(EATS)
  • 亚洲内镜与腹腔镜外科医师协会会员(ELSA)

学习、工作经历

  • 2011.7.1~2019.12.30,北京大学肿瘤医院副院长,北京肿瘤医院副院长,北京市肿瘤防治研究所副所长,胃肠肿瘤微创外科主任,主任医师
  • 1999.9.1~2008.4.1,北京大学肿瘤医院,胃肠外科 副主任医师
  • 1996.9.1~1999.7.31,北京肿瘤医院(北京市肿瘤防治研究所),硕士研究生
  • 1996.9.1~2000.7.31,北京肿瘤医院(北京市肿瘤防治研究所),硕士研究生
  • 2000.9.1~2008.4.1,北京大学肿瘤医院,胃肠外科 副主任医师
  • 2000.9.1~2008.4.6,北京大学肿瘤医院,胃肠外科 副主任医师
  • 2001.4.1~2014.2.18,北京大学肿瘤医院,胃肠外科 副教授
  • 2001.4.1~2014.2.18,北京大学肿瘤医院,胃肠外科 副教授
  • 2008.4.1~2009.4.6,北京大学肿瘤医院,胃肠外科 主任医师
  • 2008.4.1~2009.4.20,北京大学肿瘤医院,胃肠外科 主任医师