学术论文 | 奖励表彰 | 科研项目
Ziqian Deng#, Ting Guo#, Jiwang Bi, Gangjian Wang, Ying Hu, Hong Du, Yuan Zhou*, Shuqin Jia*, Xiaofang Xing* and Jiafu Ji*, Transcriptome profiling of patient-derived tumor xenografts suggests novel extracellular matrix-related signatures for gastric cancer prognosis prediction,Journal of Translational Medicine,(2023) 21:638
Ma X#, Jia S#, Wang G#, Liang M, Guo T, Du H, Li S, Li X, Huangfu L, Guo J, Xing X, Ji J. TRIM28 promotes the escape of gastric cancer cells from immune surveillance by increasing PD-L1 abundance,Signal transduction and targeted therapy,
Zhang M, Yang H, Fu T, Meng M, Feng Y, Qu C, Li Z, Xing X, Li W, Ye M, Li S, Bu Z*, Jia S*. Liquid biopsy: circulating tumor DNA monitors neoadjuvant chemotherapy response and prognosis in stage II/III gastric cancer.,Molcecular Oncology,doi: 10.1002/1878-0261.13481
Zhang M, Feng Y, Qu C, Meng M, Li W, Ye M, Li S, Li S, Ma Y, Wu N, Jia S. Comparison of the somatic mutations between circulating tumor DNA and tissue DNA in Chinese patients with non-small cell lung cancer,The International journal of biological markers,
Li Z, Jia Y, Zhu H, Yuan H, Xing X, Xin Y, Ma T, Pang F, Zhang Y, Hu Y, Jia S*, Ji J*. Genomic landscape of microsatellite instability in Chinese tumors: a comparison of Chinese and TCGA cohorts,International journal of cancer Journal international du cancer,
Xing X#, Shi J#, Jia Y#, Dou Y#, Li Z#, Dong B, Guo T, Cheng X, Li X, Du H, Hu Y, Jia S*, Zhang J*, Li Z*, Ji J*.Effect of neoadjuvant chemotherapy on the immune microenvironment in gastric cancer as determined by multiplex immunofluorescence and T cell receptor repertoire analysis.,J Immunother Cancer,10(3):e003984
Zhang M, Qi C, Wang Z, Chen H, Zhao X, Zhang X, Zhou Y, Gao C, Bai Y, Jia S*, Ji J*. Molecular characterization of ctDNA from Chinese patients with advanced gastric adenocarcinoma reveals actionable alterations for targeted and immune therapy,Journal of molecular medicine,
Guo T, Bai YH, Cheng XJ, Han HB, Du H, Hu Y, Jia SQ*, Xing XF*, Ji JF*. Insulin gene enhancer protein 1 mediates glycolysis and tumorigenesis of gastric cancer through regulating glucose transporter 4,Cancer communications,
Jia X, Guo T, Li Z, Zhang M, Feng Y, Dong B, Li Z, Hu Y, Li Z, Xing X*, Jia S*, Ji J*. Clinicopathological and Immunomicroenvironment Characteristics of Epstein-Barr Virus-Associated Gastric Cancer in a Chinese Population,Frontiers in oncology,
Zhang Y, Yao Y, Xu Y, Li L, Gong Y, Zhang K, Zhang M, Guan Y, Chang L, Xia X, Li L, Jia S*, Zeng Q*. Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients,Nature communications,
Han H, Wang S, Meng J, Lyu G, Ding G, Hu Y, Wang L, Wu L, Yang W, Lv Y, Jia S*, Zhang L*, Ji J*. Long noncoding RNA PART1 restrains aggressive gastric cancer through the epigenetic silencing of PDGFB via the PLZF-mediated recruitment of EZH2,Oncogene,
Xing X#, Jia S#, Leng Y#, Wang Q#, Li Z, Dong B, Guo T, Cheng X, Du H, Hu Y, Feng Q, Lian S, Luan F, Ma X, Li Z, Ni M, Li Z, Ji J. An integrated classifier improves prognostic accuracy in non-metastatic gastric cancer,Oncoimmunology,
中华医学会医学科学技术奖, 一等奖, 第1完成人, 中华医学会, 2025.1
临床决策支持系统研发与全自动一体化系统临床应用评估, 课题负责人, 2022.11.1~2027.9.30, 科技部十四五重点研发计划
E3泛素连接酶Trim28通过稳定TBK1调控胃癌免疫微环境导致紫杉醇耐药的机制研究, 课题负责人, 2021.1.1~2024.12.31, 国家自然科学基金面上项目
应用DNA错配修复缺陷及微卫星不稳定状态对局部进展期胃癌新辅助化疗开展分子评效的观察性研究, 课题负责人, 2018.1.1~2020.12.1, 首都卫生发展科研专项项目
胃癌免疫抑制微环境标志物AEBP1的临床检测及作用机制研究, 参加者, 2025.1.1~2027.12.31, 国家自然科学基金青年科学基金
基于影像-病理-多组学的MSI-H/dMMR胃癌双特异性单抗免疫治疗疗效智能预测研究, 参加者, 2023.1.1~2026.12.31, 国家自然科学基金重大研究计划项目
基于胃癌临床队列的多组学分子网络谱图绘制及关键治疗靶点的机制探索, 参加者, 2021.1.1~2024.12.31, 国家自然科学基金
肿瘤的多学科协作临床决策支持系统研发与实践-精准医疗临床决策支持系统研发, 参加者, 2018.7.1~2022.12.31, 科技部十三五重点研发计划
真实世界实体瘤ctDNA基因变异检出率及其与组织一致性的研究, 参加者, 2023.1.1~2025.12.31, 北京市属医院科研培育计划
紫杉醇对胃癌中PDL1表达及免疫微环境的调控机制及联合治疗模式探索, 参加者, 2019.1.1~2022.12.31, 国家自然科学基金