学术论文 | 科研项目 | 招生计划
Guo X, Zhang Y, Zhang Z, Lu L, Liu Y, Li Z, Zhou T, Zhang J, Li W, You W, Tao G, Chen W, Zeng H, Pan K. Gastric cancer-associated long non-coding RNA profiling and noninvasive biomarker screening based on a high-risk population cohort,Cancer Med.,12(11):12728-12738.
Huang S, Guo Y, Li ZW, Shui GH, Tian H, Li BW, Kadeerhan G, Li ZX, Li X, Zhang Y, Zhou T, You WC, Pan KF*, Li WQ*. Identification and validation of plasma metabolomic signatures in precancerous gastric lesions that progress to cancer.,JAMA Network Open,4(6):e2114186
Guo Y#, Zhang Y#, Gerhard M, Gao JJ, Mejias-Luque R, Zhang L, Vieth M, Ma JL, Bajbouj M, Suchanek S, Liu WD, Ulm K, Quante M, Li ZX, Zhou T, Schmid R, Classen M, Li WQ, You WC*, Pan KF*. Effect of Helicobacter pylori on gastrointestinal microbiota: a population-based study in Linqu, a high-risk area of gastric cancer.,Gut,69(9):1598-1607.
Liu ZC#, Wu WH#, Huang S, Li ZW, Li X, Shui GH, Lam SM, Li BW, Li ZX, Yang Zhang, Zhou T, You WC, Pan KF*, Li WQ*. Plasma lipids signify the progression of precancerous gastric lesions to gastric cancer: a prospective targeted lipidomics study,Theranostics,Vol. 12, Issue 10
Li X, Zheng NR, Wang LH, Li ZW, Liu ZC, Fan H, Wang Y, Dai J, Ni XT, Wei X, Liu MW, Li K, Li ZX, Zhou T, Zhang Y, Zhang JY, Kadeerhan G, Huang S, Wu WH, Liu WD, Wu XZ, Zhang LF, Xu JM, Gerhard M, You WC, Pan KF*, Li WQ*, Qin J*. Proteomic profiling identifies signatures associated with progression of precancerous gastric lesions and risk of early gastric cancer,EBioMedicine,74:103714
Guo Y#, Li ZX#, Zhang JY, Ma JL, Zhang L, Zhang Y, Zhou T, Liu WD, Han ZX, Li WQ*, Pan KF*, You WC. Association Between Lifestyle Factors, Vitamin and Garlic Supplementation, and Gastric Cancer Outcomes: A Secondary Analysis of a Randomized Clinical Trial,JAMA Netw Open,3(6):e206628
Kadeerhan G, Gerhard M, Gao JJ, Mejías-Luque R, Zhang L, Vieth M, Ma JL, Bajbouj M, Suchanek S, Liu WD, Ulm K, Quante M, Li ZX, Zhou T, Schmid R, Classen M, Li WQ, Zhang Y, You WC, Pan KF. Microbiota alteration at different stages in gastric lesion progression: a population-based study in Linqu, China,Am J Cancer Res,11(2):561-575
Fan X, Qin X, Zhang Y, Li Z, Zhou T, Zhang J, You W, Li W, Pan K*. Screening for gastric cancer in China: Advances, challenges and visions.,Chin J Cancer Res,33(2):168-180
Li ZX, Ma JL, Guo Y, Liu WD, Li M, Zhang LF, Zhang Y, Zhou T, Zhang JY, Gao HE, Guo XY, Ye DM, Li WQ, You WC, Pan KF*. Suppression of Helicobacter pylori infection by daily cranberry intake: A double-blind, randomized, placebo-controlled trial.,J Gastroenterol Hepatol,36(4):927-935
Huang S, Guo Y, Li Z, Zhang Y, Zhou T, You W, Pan K, Li W. A systematic review of metabolomic profiling of gastric cancer and esophageal cancer,Cancer Biol Med,17(1):181-198
Shi Y, Zhang Y, Zhang L, Ma JL, Zhou T, Li ZX, Liu WD, Li WQ, Deng DJ, You WC, Pan KF. Telomere Length of Circulating Cell-Free DNA and Gastric Cancer in a Chinese Population at High-Risk.,Frontiers in Oncology,9: 1434
Dai J, Nishi A, Li ZX, Zhang Y, Zhou T, You WC, Li WQ*, Pan KF*. DNA methylation signatures associated with prognosis of gastric cancer.,BMC Cancer,21(1):610
Tan XH, Zhao M, Pan KF, Dong Y, Dong B, Feng GJ, Jia G, Lu YY. Frequent mutation related with over expression of DNA polymerase beta in primary tumors and precancerous lesions of human stomach,Cancer Letters,220:101–114
You WC, Hong JY, Zhang L, Pan KF, Pee D, Li JY, Ma JL, Rothman N, Caporaso N, J Fraumeni Jr, Xu GW,. Gail MH. Genetic polymorphisms of CYP2EI, GSTTI, GSTPI, GSTMI, ALDH2, and ODC and the risk of advanced precancerous gastric lesions in a Chinese population,Cancer Epidemiol, Biomarks & Prev,14:451-458
Huang S, Guo Y, You WC, Pan KF, Li WQ. A systematic review on metabolomic profiling of human gastric cancer and esophageal cancer.,Cancer Biology & Medicine,
Shi Y#, Zhang Y#, Zhang L, Ma JL, Zhou T, Li ZX, Liu WD, Li WQ, Deng DJ, You WC*, Pan KF*. Telomere Length of Circulating Cell-Free DNA and Gastric Cancer in a Chinese Population at High-Risk,Frontiers in Oncology,9: 1434
Guo Y#, Li ZX#, Zhang JY, Ma JL, Zhang L, Zhang Y, Zhou T, Liu WD, Han ZX, Li WQ*, Pan KF*, You WC. Association Between Lifestyle Factors, Vitamin and Garlic Supplementation, and Gastric Cancer Outcomes: A Secondary Analysis of a Randomized Clinical Trial,JAMA Netw Open,3(6):e206628
Guo Y#, Zhang Y#, Gerhard M, Gao JJ, Mejias-Luque R, Zhang L, Vieth M, Ma JL, Bajbouj M, Suchanek S, Liu WD, Ulm K, Quante M, Li ZX, Zhou T, Schmid R, Classen M, Li WQ, You WC*, Pan KF*. Effect of Helicobacter pylori on gastrointestinal microbiota: a population-based study in Linqu, a high-risk area of gastric cancer,Gut,pii: gutjnl-2019-319696
根除幽门螺杆菌预防胃癌大规模人群干预研究——胃镜随访研究, 课题负责人, 2018.10.1~2028.12.31, 中德国际合作项目
胃内菌群动态变化与胃黏膜病变演变的关系研究, 课题负责人, 2022.1.1~2025.12.31, 国家自然科学基金
上消化道癌分级筛查及干预方案评价研究, 课题负责人, 2018.9.1~2020.12.31, 科技部重点研发项目 2018YFC1313105
幽门螺杆菌感染相关胃癌标志物的筛选及在中-德人群中的验证, 课题负责人, 2019.1.1~2021.12.31, 国家自然基金委 81861138041
胃癌、食管癌预防及干预策略研究, 课题负责人, 2019.1.1~2019.12.31, 北京市财政
登峰计划, 课题负责人, 2018.1.1~2021.12.30, 北京市医管局
国家自然科学基金, 课题负责人, 2016.1.1~2019.12.31, 国家自然科学基金委(81572811)
社会任职
- 中华预防医学会肿瘤预防与控制专业委员会 副主任委员
- 中国抗癌协会癌症筛查与早诊早治专业委员会 副主任委员
- 中国抗癌协会肿瘤流行病学专业委员会 副主任委员
- 国家自然基金委评审专家
- 国际胃癌协会 委员
学习、工作经历
- 2016.1.12~2022.6.1,科研副院长
- 2014.8.1~,北京大学肿瘤医院 流行病学研究室 教授
- 2012.7.1~,北京大学肿瘤医院 流行病学研究室 研究室主任
- 2008.10.1~,北京大学肿瘤医院 流行病学研究室 研究员