Xuehong Zhang(#), Paiyun Li(#), Ying Gan, Shengyan Xiang, Liankun Gu, Jing Zhou, Xiaorui Zhou, Peihuang Wu, Baozhen Zhang(*), Dajun Deng. Driving effect of P16 methylation on telomerase reverse transcriptase-mediated immortalization and transformation of normal human fibroblasts.,Chinese Medical Journal,

Xiaotao Wang(#), Jie Xu, Baozhen Zhang, Ye Hou, Fan Song, HuijueLyu, Feng Yue(*).Genome-wide detection of enhancer-hijacking events from chromatin interaction data in rearranged genomes.,Nature Methods,18(6): 661–668

Tejaswi Iyyanki#; Baozhen Zhang#; Qixuan Wang#; Ye Hou#; QiushiJin; Jie Xu; Hongbo Yang; Tingting Liu; Xiaotao Wang; Fan Song; Yu Luan; Hironobu Yamashita; Ruby Chien; HuijueLyu; Lijun Zhang; Lu Wang; Joshua Warrick; Jay D. Raman; Joshua J. Meeks; David J. DeGraff*; Feng Yue*. Subtype-associated epigenomic landscape and 3D genome structure in bladder cancer.,Genome Biology,2021,22(1): 105.

Jie Xu(#), Fan Song(#), Huijue Lyu, Mikoto Kobayashi, Baozhen Zhang, Ziyu Zhao, Ye Hou, Xiaotao Wang, Yu Luan, Bei Jia, Lena Stasiak, Josiah Hiu-yuen Wong, Qixuan Wang, Qi Jin, QiushiJin, Yihao Fu, Hongbo Yang, Ross C. Hardison, Sinisa Dovat, Leonidas C. Platanias, YaruiDiao, Yue Yang, Tomoko Yamada, Aaron D. Viny, Ross L. Levine, David Claxton, James. R. Broach, Hong Zheng(*), Feng Yue(*). Subtype-specific 3D genome alteration in acute myeloid leukaemia.,Nature,611(7935):387-398.

Paiyun Li(#), Ying Gan(#), Sisi Qin, Xiao Han, Chenghua Cui, Zhaojun Liu, Jing Zhou, Liankun Gu, Zhe-Ming Lu, Baozhen Zhang(*), Dajun Deng(*), DNA hydroxymethylation increases the susceptibility of reactivation of methylated P16 alleles in cancer cells.,Epigenetics,2020,15(6-7):618-631.

肿瘤的表观遗传学研究

一个CDKN2A/P16基因新增强子的鉴定和功能研究, 课题负责人, 2021.1.1～2024.12.31, 国家自然科学基金面上项目

DNA甲基化通过诱发染色质构象改变促进P16基因拷贝缺失发生的作用及其机制, 课题负责人, 2022.1.1～2024.12.31, 北京市自然科学基金

p16启动子DNA甲基化诱导细胞永生化和恶性转化作用及其机制, 课题负责人, 2018.1.1～2021.12.31, 国家自然科学基金委员会，面上项目

CDH1基因启动子区-73SNP影响DNA甲基化的机制, 课题负责人, 2016.1.1～2019.12.31, 国家自然科学基金委员会，面上项目