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导师基本信息

  • 姓名:朱华
  • 性别:
  • 民族:汉族
  • 科室:核医学科
  • 职称:副研究员
  • 专业:影像医学与核医学
  • E-MAIL: zhuhuananjing@163.com

学术论文 | 研究方向 | 科研项目 | 招生计划

Nina Zhou#, Chang Liu#, Xiaoyi Guo#, Yuping Xu, Jifang Gong, Changsong Qi, Xiaotian Zhang, Ming Yang*, Hua Zhu*, Lin Shen*, Zhi Yang*. 68Ga-NOTA-MAL- MZHER2 PET Imaging in advanced gastric cancer patients and therapeutic response monitoring.,European Journal of Nuclear Medicine and Molecular Imaging,,2021, 48, 161-175

Shujing Wang#, Hua Zhu#,*, Jin Ding, Feng Wang, Lixin Ding, Yan Zhang, Nan Li, Sheng Yao, Xinan Sheng*, Zhi Yang*. Positron Emission Tomography Imaging of Programmed Death 1 Expression in Cancer Patients Using Iodine-124 Labeled Toripalimab: A Pilot Clinical Translation Study.,Clinical Nuclear Medicine,2021, 46(5), 382-388

Xiaoyi Guo#, Nina Zhou#, Zuhua Chen#, Teli Liu, Xiaoxia Xu, Xia Lei, Lin Shen, Jing Gao, Zhi Yang*, Hua Zhu*. Construction of 124I-trastuzumab for Noninvasive PET Imaging of HER2 Expression: From Patient-derived Xenograft Models to Gastric Cancer Patients.,Gastric Cancer.,2020. 23:614-626. (SCI IF 5.55 Q1 )

Chen Liu?, Teli Liu?, Zhongyi Zhang?, Ning Zhang, Peng Du, Yong Yang, Yiqiang Liu, Wei Yu, Nan Li, Michael A Gorin, Steven P. Rowe*, Hua Zhu*, Kun Yan*, Zhi Yang*. PSMA PET/CT and standard plus PET/CT-Ultrasound fusion targeted prostate biopsy can diagnose clinically significant prostate cancer in men with previous negative biopsies.,Journal of Nuclear Medicine,,2020. DOI: 10.2967/jnumed.119.235333. (Q1, SCI 7.439).

Nina Zhou?, Xiaoyi Guo?, Min Yang, Hua Zhu*, Zhi Yang*.68Ga-ZHER2 PET/CT Reveals HER2-positive Metastatic Gastric Cancer with Better Image Quality than 18F-FDG.,Clinical Nuclear Medicine,,2020, DOI 10.1097/RLU.0000000000002859. (SCI IF 6.5 Q1 )

Xiaoxia Xu?, Hua Zhu?, Fei Liu, Yan Zhang, Jianhua Yang, Lifang Zhang, Qing Xie, Lin Zhu, Nan Li*, Hank F. Kung*, Zhi Yang*. Dynamic PET/CT imaging of 18F-(2S, 4R)4-fluoroglutamine in healthy volunteers and oncological patients.,European Journal of Nuclear Medicine and Molecular Imaging,,2020, DOI: 10.1007/s00259-019-04543-w. (SCI IF 7.7 Q1 )

Haifeng Huang?, Hua Zhu?, Quan Xie, Xiao-Bin Tian, Xian-Teng Yang, Fan Feng, Qi-Yu Jiang, Xi-Nan Sheng, Zhi Yang*. Evaluation of 124I-JS001 for hPD1 immuno-PET imaging using sarcoma cell homografts in humanized mice.,Acta Pharmaceutica Sinica B.,2020, DOI: 10.1016/j.apsb.2020.02.004. (SCI IF 6.01 Q1 )

Fei Liu, Xiaoyi Guo, Teli Liu, Xiaoxia Xu, Nan Li, Chiyi Xiong, Chun Li, Hua Zhu*, Zhi Yang*. Evaluation of Pan-SSTRs Targeted Radioligand [64Cu]NOTA-PA1 Using Micro-PET Imaging in Xenografted Mice.,ACS Med. Chem. Lett.,2020, 11, 445-450. (SCI IF 3.74, Q2)

王风,郭晓轶,刘特立,丁立新,夏雷,丁缙,孟祥溪,蒋金泉,朱华*,杨志. 固体靶PET核素89Zr的制备、质控和抗体标记.,中华核医学与分子影像杂志,2020, 40 (5):294-297.

Xudong Wang?, Feng Wang?, Jintao Han, Zhi Yang, Hua Zhu,* Gen Yang*. Construction and Preclinical Evaluation of a 124/131I?Labeled Radiotracer for the Detection of Mesothelin-Overexpressing Cancer. Molecular Pharmaceutics. 2020. 17, 1875-1883. (Q1, SCI, 4.4),Molecular Pharmaceutics,. 2020. 17, 1875-1883. (Q1, SCI, 4.4)

Nina Zhou?, Chang Liu?, Xiaoyi Guo?, Yuping Xu, Jifang Gong, Changsong Qi, Xiaotian Zhang, Ming Yang*, Hua Zhu*, Lin Shen*, Zhi Yang*. 68Ga-NOTA-MAL- MZHER2 PET Imaging in advanced gastric cancer patients and therapeutic response monitoring.,European Journal of Nuclear Medicine and Molecular Imaging,,2020, DOI: 10.1007/s00259-020-04898-5. (SCI IF 7.7 Q1 )

F Liu, TL Liu; XX Xu, XY Guo, N Li, CY Xiong, C Li, H Zhu*, Z Yang*. Design, Synthesis and Biological Evaluation of 68Ga-DOTA-PA1 for Lung Cancer: A Novel PET Tracer for Multiple Somatostatin Receptors Imaging.,Molecular Pharmaceutics. 2018. 15, 619−628. (SCI IF 4.4).,. 2018. 15, 619−628. (SCI IF 4.4).

F Liu†, H Zhu†, JY Yu, XD Han, QH Xie, TL Liu, CQ Xia, N Li*, Z Yang*. 68Ga/177Lu-labeled DOTA-TATE show similar imaging andbiodistribution in neuroendocrine tumor model,Tumor Biology ,2017, TUBI-D-16-04135.

Xie QH†, Zhu H†, Wang F, Meng XX, Ren QS, Xia CQ *, Yang Z*.Establishing Reliable 64Cu Production Process: From Target Plating to Molecular Specific Tumor Micro-PET Imaging.,Molecules ,2017, 22, 641 (doi:10.3390/molecules22040641)

Hua Zhu†, Chuanke Zhao†, Fei Liu, Lixin Wang, Junnan Feng, Chengchao Shou*, Zhi Yang*. 125I-F56 peptide as radio-analysis agent targeting VEGFR1 in mice xenografted with human gastric tumor.,ACS Med. Chem. Lett. ,2017, 8, 266-269. (20170120)

C Liu, TL Liu, N Zhang, YQ Liu, N Li, P Du, Y Yang, M Liu, K Gong, X Yang, H Zhu*, K Yan, Z Yang*. 68Ga-PSMA-617 PET/CT: a promising new technique for predicting risk stratification and metastatic risk of prostate cancer patients.,European Journal of Nuclear Medicine and Molecular Imaging,,2018, (DOI: 10.1007/s00259-018-4037-9).

下一代”PET 核素探针的研发及指导肿瘤免疫治疗的临床转化, 课题负责人 , 2020.1.1~2021.12.31, 北京市百千万人才工程培养经费资助A类

生物学可控的Her-MNP纳米平台的构建、评价及分子显像的研究。, 课题负责人 , 2017.1.1~2020.12.31, 国家自然科学基金面上项目 (No. 81671733)

神经内分泌肿瘤特异性多功能纳米分子探针NIRF-CCPM-Octreotide的研究, 课题负责人 , 2015.1.1~2017.12.31, 国家自然科学基金青年基金 (No. 81401467)

新型64Cu核素的制备及64Cu-DOTA-TATE探针在NET诊疗的应用。, 课题负责人 , 2017.1.1~2019.12.31, 北京市科学技术委员会“2017年北京市科技新星计划”(xx2017016)。

新型固体靶PET核素探针在胃肠肿瘤的转化研究, 课题负责人 , 2018.1.1~2020.12.31, 北京市委组织部 2017000021223ZK33

国家重点研发计划“重大慢性非传染性疾病防控研究”专项。“胃癌靶向治疗新技术研究”项目, 参加者 , 2017.7.1~2020.12.31, 科技部,2017YFC1308903

HER2靶向PET探针的构建及其指导肿瘤精准诊疗的临床转化。, 课题负责人 , 2019.1.8~2019.12.8, 北京市自然科学基金 京津冀基础研究合作专项。(H2018206600)

研究生招生计划
招生年度 招生专业 学位级别 学位类型 研究方向 选拔方式
2022 影像医学与核医学 硕士 科学学位 核医学分子影像,放射性药物 全国统考

社会任职

  • 全国高等院校本科临床医学专业国家化教育“十三五”规划教材《核医学》编委
  • 中国核学会放射性药物分会秘书长

学习、工作经历

  • 2015.8.1~2016.6.20,北京大学肿瘤医院核医学科副研究员
  • 2014.11.1~2015.11.1,美国斯坦福大学药学院放射治疗系访问学者
  • 2011.8.1~2015.7.1,北京大学肿瘤医院核医学科助理研究员
  • 2007.9.1~2011.7.1,中国科学院上海应用物理研究所(硕博连读)理学博士
  • 2002.9.1~2006.6.1,南京师范大学化学与环境科学学院理学学士