学术论文 | 奖励表彰 | 专利 | 科研项目 | 招生计划
Chaoting Zhang#, Ting Liu#, Shance Li, Xia Teng, Yuge Zhu, Guanyu Zhang, Huimin Xie, Kang Sun, Jiaxin Tu, Wenjun Yang*, Zheming Lu* Membrane-bound IL-7 immobilized by the CD8 transmembrane region improves efficacy of CD19 CAR-T cell therapy,Molecular Cancer,(2024) 23:236
Rui Guo, Zhili Li, Jiahao Shi, Haiyang Yong, Chenfei Wang*, Jianzhong Li*, Chaoting Zhang*, Dezhong Zhou* Hyaluronic acid coating of poly(β-amino ester)/mRNA polyplexes enables ultra-high transfection efficiency,Journal of Controlled Release,2024 Dec 20:378:428-437
Chaoting Zhang#, Yizhe Sun#, Shance Li, Luyan Shen, Xia Teng, Yefei Xiao, Nan Wu*, Zheming Lu* Autophagic flux restoration enhances the antitumour efficacy of tumour infiltrating lymphocytes,Journal for ImmunoTherapy of Cancer,2022 Oct;10(10):e004868
Chaoting Zhang#, Qin Tan#, Shance Li#, Luyan Shen, Jingtao Zhang, Ying Liu, Wenjun Yang*, Zheming Lu*. Induction of EBV latent membrane protein-2A (LMP2A) specific T cells and construction of individualized TCR-engineered T cells for EBV associated malignancies.,Journal for Immunotherapy of Cancer,2021 Jul;9(7):e002516.
Hui Liu#, Wen Lei#, Chaoting Zhang#, Chunmei Yang, Juying Wei, Qunyi Guo, Xiaojun Guo, Zhilu Chen, Ying Lu, Ken H Young*, Zheming Lu*, Wenbin Qian*. CD19-Specific CAR-T Cells that Express a PD-1/CD28 Chimeric Switch-Receptor is Effective in Patients with PD-L1 Positive B-Cell Lymphoma,Clinical cancer research,2021 Jan 15;27(2):473-484.
Chaoting Zhang#, Heyilimu Palashati#, Zhuona Rong, Ningjing Lin, Luyan Shen, Ying Liu, Shance Li, Bentong Yu*, Wenjun Yang*, Zheming Lu*. Pre-depletion of TRBC1+ T cells promotes the therapeutic efficacy of anti-TRBC1 CAR-T for T-cell malignancies,Molecular cancer,2020, 19:162
Chaoting Zhang#, Shance Li#, Luyan Shen, Xia Teng, Yefei Xiao, Wenjun Yang*, Zheming Lu* Single-cell sequencing of tumour infiltrating T cells efficiently identifies tumour-specific T cell receptors based on the T cell activation score,Cancer Immunology, Immunotherapy,2024 May 10;73(7):123
Shance Li#, Chaoting Zhang#, Luyan Shen, Xia Teng, Yefei Xiao, Bentong Yu*, Zheming Lu* TCR extracellular domain genetically linked to CD28, 2B4/41BB and DAP10/CD3ζ -engineered NK cells mediates antitumor effects.,Cancer Immunology, Immunotherapy,2023 Mar;72(3):769-774
Chaoting Zhang#, Yizhe Sun#, Shance Li, Luyan Shen, Xia Teng, Yefei Xiao, Ping Zhou*, Zheming Lu* Autophagic flux restoration of senescent T cells improves antitumor activity of TCR-engineered T cells.,Clin Transl Immunology,2022 Sep 26;11(9):e1419.
社会任职
- 北京抗癌协会食管癌专业委员会委员
- 北京肿瘤医院伦理委员会委员
学习、工作经历
- 2023.8.1~,北京大学肿瘤医院 生化与分子生物学研究室 副教授
- 2019.8.1~,北京大学肿瘤医院 生化与分子生物学研究室 副研究员
- 2017.8.1~2019.7.31,北京大学肿瘤医院 生化与分子生物学研究室 助理研究员
- 2012.9.1~2017.7.1,北京大学医学部 肿瘤学博士
- 2007.9.1~2012.7.1,北京大学医学部 医学学士