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导师基本信息

  • 姓名:李文庆
  • 性别:
  • 民族:汉族
  • 科室:流行病学研究室
  • 职称:研究员
  • 专业:流行病与卫生统计学
  • E-MAIL: wenqing_li@bjmu.edu.cn

学术论文 | 综述述评 | 出版专著 | 奖励表彰 | 研究方向 | 专利 | 科研项目

Li WQ, Zhang JY, Ma JL, Li ZX, Zhang L, Zhang Y, Guo Y, Zhou T, Li JY, Shen L, Liu WD, Han ZX, Blot WJ, Gail MH, Pan KF, You WC. Effects of Helicobacter pylori treatment and vitamin and garlic supplementation on gastric cancer incidence and mortality: follow-up of a randomized intervention trial,BMJ,366:l5016. doi: 10.1136/bmj.l5016.

Fan H#, Li X#, Li ZW, Zheng NR, Cao LH, Liu ZC, Liu MW, Li K, Wu WH, Li ZX, Zhou T, Zhang Y, Liu WD, Zhang LF, You WC, Wang Y, Wu J*, Pan KF*, Qin J*, Li WQ*. Urine proteomic signatures predicting the progression from premalignancy to malignant gastric cancer.,eBioMedicine,2022;86: 104340

Liu ZC#, Wu WH#, Huang S, Li ZW, Li X, Shui GH, Lam SM, Li BW, Li ZX, Zhang Y, Zhou T, You WC, Pan KF*, Li WQ*. Plasma lipids signify the progression of precancerous gastric lesions to gastric cancer: a prospective targeted lipidomics study,Theranostics,12(10):4671-4683.

Li X#, Zheng NR#, Wang LH#, Li ZW, Liu ZC, Fan H, Wang Y, Dai J, Ni XT, Wei X, Liu MW, Li K, Li ZX, Zhou T, Zhang Y, Zhang JY, Kadeerhan G, Huang S, Wu WH, Liu WD, Wu XZ, Zhang LF, Xu JM, Gerhard M, You WC, Pan KF*, Li WQ*, Qin J*. Proteomic profiling identifies signatures associated with progression of precancerous gastric lesions and risk of early gastric cancer.,EbioMedicine,2021 Nov 21;74:103714.

Huang S, Guo Y, Li ZW, Shui GH, Tian H, Li BW, Kadeerhan G, Li ZX, Li X, Zhang Y, Zhou T, You WC, Pan KF*, Li WQ*. Identification and validation of plasma metabolomic signatures in precancerous gastric lesions that progress to cancer.,JAMA Network Open,4(6):e2114186

Dai J*, Dai W, Li WQ*. Trends in physical activity and sedentary time among U.S. adults with diabetes: 2007–2020.,Diabetes Metab Syndr,17(10): 102874

Li WQ#, Qin XX#, Li ZX, Wang LH, Liu ZC, Fan XH, Zhang LH, Li Y, Wu XZ, Ma JL, Zhang Y, Zhang LF, Li M, Zhou T, Zhang JY, Wang JX, Liu WD, You WC, Pan KF*. Beneficial effects of endoscopic screening on gastric cancer and its optimal screening interval: a population-based study.,Endoscopy,doi: 10.1055/a-1728-5673.

Su XQ, Yin ZY, Jin QY, Liu ZC, Han X, Hu ZQ, Zhang L, Ma JL, Li ZX, Zhang Y, Zhou T, Liu WD, You WC, Pan KF, Shi L*, Li WQ*. Allium vegetable intake associated with risk of incident gastric cancer: a continuous follow-up study of a randomized intervention trial,American Journal of Clinical Nutrition,2023 Jan; 117(1): 22-32.

Dai J(#); Li TY; Cho E; Qureshi AA; Li WQ(*). Hair Color and Risk of Keratinocyte Carcinoma in US Women and Men.,J Am Acad Dermatol,86(1):234-237.

Wu WH, Geng H, Cho E, Eliassen AH, Drucker AM, Li TY, Qureshi AA, Li WQ*. Reproductive and hormonal factors and risk of incident rosacea among US white women.,J Am Acad Dermatol,87(1):138-140

Fan X#, Qin X, Zhang Y, Li Z, Zhou T, Zhang J, You W, Li W*, Pan K*. Screening for gastric cancer in China: Advances, challenges and visions.,Chin J Cancer Res,33(2):168-180.

Xue Li #, Kaifeng Pan, Michael Vieth, Markus Gerhard , Wenqing Li*, and Raquel Mejiías-Luque*. JAK-STAT1 Signaling Pathway Is an Early Response to Helicobacter pylori Infection and Contributes to Immune Escape and Gastric Carcinogenesis,International Journal of Molecular Sciences,2022 Apr 8;23(8):4147.

Huai P, Liu J, Ye X and Li W-Q. Association of Central Obesity With All Cause and Cause-Specific Mortality in US Adults: A Prospective Cohort Study.,Front. Cardiovasc. Med,9:816144. doi: 10.3389/fcvm.2022.816144

Fan XH, Zhang Y, Wang P, Song QQ, Wang M, Mejias-Luque R, Li ZX, Zhou T, Zhang JY, Liu WD, Zhang LF, Li WQ, You WC, Gerhard M, Jiao YC, Wang XB*, Pan KF*. A noninvasive multianalytical approach establishment for risk assessment and gastric cancer screening.,Int J Cancer.,2023 Oct 16. doi: 10.1002/ijc.34739.

Peng L, Guo Y, Gerhard M, Gao JJ, Liu ZC, Mejías-Luque R, Zhang L, Vieth M, Ma JL, Liu WD, Li ZX, Zhou T, Li WQ, You WC, Zhang Y*, Pan KF*. Metabolite Alterations and Interactions with Microbiota in Helicobacter pylori-Associated Gastric Lesions,Microbiol. Spectr.,e0534722

Melough MM, Wu S, Li WQ, Eaton C, Nan H, Snetselaar L, Wallace R, Qureshi AA, Chun OK, Cho E. Citrus Consumption and Risk of Cutaneous Malignant Melanoma in the Women's Health Initiative,Nutrition and Cancer-an International Journal,72(4): 568-575

Zheng K, Zhu X, Fu S, Cao G, Li WQ, Xu L, Chen H, Wu D, Yang R, Wang K, Liu W, Wang H, Bao Q, Liu M, Hao C, Shen L, Xing B, Wang X. Sorafenib Plus Hepatic Arterial Infusion Chemotherapy versus Sorafenib for Hepatocellular Carcinoma with Major Portal Vein Tumor Thrombosis: A Randomized Trial.,Radiology.,2022 Feb 1:211545.

Xu HM, Li WQ*. Early detection of gastric cancer in China: progress and opportunities.,Cancer Biology & Medicine,2022 Dec 12;19(12):1622–8.

Wenhui W, Zongchao L, Zhexuan L, Weidong L, Lanfu Z, Yang Z, Tong Z, Weicheng Y, Kaifeng P*, Wenqing L*. Effects of Helicobacter pylori eradication on the profiles of blood metabolites and their associations with the progression of gastric lesions: a prospective follow-up study,Cancer Biology & Medicine,2022 Aug 30;19(8):1259–73

Shi Y, Zhang Y, Zhang L, Ma JL, Zhou T, Li ZX, Liu WD, Li WQ, Deng DJ, You WC, Pan KF. Telomere Length of Circulating Cell-Free DNA and Gastric Cancer in a Chinese Population at High-Risk,Frontiers in Oncology,9:1434.

Guo Y#, Zhang Y#, Gerhard M, Gao JJ, Mejias-Luque R, Zhang L, Vieth M, Ma JL, Bajbouj M, Suchanek S, Liu WD, Ulm K, Quante M, Li ZX, Zhou T, Schmid R, Classen M, Li WQ, You WC*, Pan KF*. Effect of Helicobacter pylori on gastrointestinal microbiota: a population-based study in Linqu, a high-risk area of gastric cancer.,GUT,pii: gutjnl-2019-319696. doi: 10.1136/gutjnl-2019-319696. [Epub ahead of print]

Kim J, Park MK, Li WQ, Qureshi AA, Cho E. Association of Vitamin A Intake With Cutaneous Squamous Cell Carcinoma Risk in the United States,JAMA Dermatology,2019 Jul 31. doi: 10.1001/jamadermatol.2019.1937.

Ye DM, Li Q, Yu T, Wang HT, Luo YH*, Li WQ*. Clinical and epidemiologic factors associated with breast cancer and its subtypes among Northeast Chinese women.,Cancer Medicine,8(17):7431-7445.

Matthews NH#, Koh M, Li WQ, Li T, Willett WC, Stampfer MJ, Christiani DC, Morris JS, Qureshi AA, Cho E*. A Prospective Study of Toenail Trace Element Levels and Risk of Skin Cancer.,Cancer Epidemiol Biomarkers Prev,28(9):1534-1543

Higgins HW II*, Cho E, Weinstock MA, Li TY, Qureshi A, Li WQ*. Gender differences, UV exposure, and risk of lentigo maligna in a nationwide healthcare population cohort study.,J Eur Acad Dermatol Venereol,J Eur Acad Dermatol Venereol

Johnson CM, Fitch K, Merola JF, Han J, Qureshi A*, Li WQ*. Plasma levels of tumour necrosis factor-α and adiponectin can differentiate patients with psoriatic arthritis from those with psoriasis.,British Journal of Dermatology,181(2):379-380. doi: 10.1111/bjd.17700.

Huang S, Guo Y, Li ZX, Zhang Y, Zhou T, You WC, Pan KF, Li WQ*. A systematic review of metabolomic profling of gastric cancer and esophageal cancer.,Cancer Biol Med,17(1):181-198.

Guo Y#, Li ZX#, Zhang JY, Ma JL, Zhang L, Zhang Y, Zhou T, Liu WD, Han ZX, Li WQ*, Pan KF*, You WC. Association between lifestyle factors, vitamin and garlic supplementation, and gastric cancer outcomes: a secondary analysis of a randomized clinical trial. . 2020;,JAMA Network Open,3(6): e206628.

Cui L, Feng D, Zhu C, Li Q, Li W, Liu B. Clinical outcomes of multifocal papillary thyroid cancer: A systematic review and meta-analysis.,Laryngoscope Investig Otolaryngol,2022 Jun 21;7(4):1224-1234

Yen H, Yen H, Drucker AM, Han J, Li WQ, Li T, Qureshi A, Cho E. COX-2 inhibitors show no preventive effect in the development of skin cancer.,J Dtsch Dermatol Ges,2022 Feb;20(2):157-166

Sun W, Rice MS, Park MK, Chun OK, Melough MM, Nan H, Willett WC, Li WQ, Qureshi AA, Cho E. Intake of Furocoumarins and Risk of Skin Cancer in 2 Prospective US Cohort Studies,J Nutr,150(6):1535-1544

Li ZX, Ma JL, Guo Y, Liu WD, Li M, Zhang LF, Zhang Y, Zhou T, Zhang JY, Gao HE, Guo XY, Ye DM, Li WQ, You WC, Pan KF. Suppression of Helicobacter pylori infection by daily cranberry intake: A double-blind, randomized, placebo- controlled trial,J Gastroenterol Hepatol,36(4):927-935

Dai J, Nishi A, Li ZX, Zhang Y, Zhou T, You WC, Li WQ*, Pan KF*. DNA methylation signatures associated with prognosis of gastric cancer,BMC Cancer,21:610

Kadeerhan G, Gerhard M, Gao JJ, Mejias-Luque R, Zhang L, Vieth M, Ma JL, Bajbouj M, Suchanek S, Liu WD, Ulm K, Quante M, Li ZX, Zhou T, Schmid R, Classen M, Li WQ, Zhang Y, You WC, Pan KF. Microbiota alteration at different stages in gastric lesion progression: a population-based study in Linqu, China.,Am J Cancer Res,11(2):561-575

Xu L, Ma Y, Yuan J, Zhang Y, Wang H, Zhang G, Tu C, Lu X, Li J, Xiong Y, Chen F, Liu X, Xue Z, Zhou M, Li WQ, Wu N, Bao J, Chen H, Lu F, Su J, Qu J; Myopic Epidemiology and Intervention Study. COVID-19 Quarantine Reveals That Behavioral Changes Have an Effect on Myopia Progression.,Ophthalmology.,2021 Nov;128(11):1652-1654.

Li Y, Li WQ, Li T, Qureshi AA, Cho E. Eye color and the risk of skin cancer.,Cancer Causes Control.,2021 Oct 23. doi: 10.1007/s10552-021-01508-z.

Drucker AM, Hollestein L, Na Y, Weinstock MA, Li WQ, Abdel-Qadir H, Chan AW. Association between antihypertensive medications and risk of skin cancer in people older than 65 years: a population-based study.,CANADIAN MEDICAL ASSOCIATION JOURNAL,2021 Apr 12;193(15):E508-E516. doi: 10.1503/cmaj.201971. PMID: 33846199;

李文庆*. 我国上消化道癌一次性内镜筛查项目成效显著,New England Journal of Medicine医学前沿,

刘宗超,李文庆*. Helicobacter pylori, Homologous-Recombination Genes, and Gastric Cancer,New England Journal of Medicine医学前沿,

李文庆. 胃癌家族史与幽门螺杆菌感染治疗,New England Journal of Medicine医学前沿,

Huang S, Guo Y, Li ZX, Zhang Y, Zhou T, You WC, Pan KF, Li WQ*. A systematic review of metabolomic profiling of gastric cancer and esophageal cancer.,Cancer Biology & Medicine,17(1): 181-198

Xu HM, Li WQ*. Early detection of gastric cancer in China: progress and opportunities.,Cancer Biol Med,2022 Dec 12;19(12):1622–8.

整合肿瘤学基础卷基础分册 副主编, 参编, 世界图书出版西安有限公司, 2021.5

流行病学研究实例(第五卷), 参编, 人民卫生出版社, 2021.6

人群队列与精准预防, 参编, 上海交通大学出版社, 2020.1

中国肿瘤青年科学家奖, 中国肿瘤青年科学家奖, 第1完成人, 中国抗癌协会, 2020.11

北京市登峰人才, 北京市登峰人才, 第1完成人, 北京市医管局, 2023.12

北京大学医学部教学优秀奖, 教学优秀奖, 第1完成人, 北京大学医学部, 2023.6

中国科协演讲比赛二等奖, 二等奖, 第1完成人, 中国科协, 2021.8

北京市优青拔尖人才, 优秀人才青年拔尖个人, 第1完成人, 北京市委组织部, 2019.10

北京大学肿瘤医院优秀教师奖, 优秀教师奖, 第1完成人, 北京大学肿瘤医院, 2023.9

根除幽门螺杆菌感染及补充维生素和大蒜素对胃癌发生和死亡风险的影响:一项随机干预试验随访研究, 十佳消化道领域临床研究(2018-2019), 第1完成人, Gasteroenterology Report, 中华胃肠外科杂志以及中华炎性肠病杂志, 2019.11

北京大学肿瘤医院专利成果奖, 专利成果奖, 第1完成人, 北京大学肿瘤医院, 2023.12

胃黏膜病变进展及胃癌相关尿蛋白标志物及其应用, 发明专利, 第1完成人, 国家知识产权局, 中国, 2023.3

一种吹气试验集气袋防漏气装置, 实用新型, 第3完成人, 中国国家知识产权局, 中国, 2023.4

国家千人计划青年项目重点资助(A类), 课题负责人, 2017.11.3~2022.7.3, 中组部第十二批千人计划

基于风险预测和筛查效果评价的胃癌二级预防策略优化, 课题负责人, 2023.1.1~2026.12.31, 国家自然科学基金委

北京市登峰人才计划, 课题负责人, 2024.1.1~2027.12.31, 北京市医管局

基于长期随访大队列的胃癌风险评估及预测预警研究, 课题负责人, 2023.1.1~2025.12.31, 北京市临床医学发展专项“扬帆”计划

青年拔尖人才项目200万经费, 课题负责人, 2024.1.1~2027.12.31, 北京大学肿瘤医院

胃内微生态与胃癌发生和预后的关系, 课题负责人, 2019.12.3~2021.12.31, 北京市委组织部

皮肤T细胞淋巴瘤基于分子分型的治疗策略研究, 子课题负责人, 2024.1.1~2026.12.31, 首都卫生发展科研专项重点攻关项目

胃黏膜病变演变与胃癌发生的代谢组学分子标签, 课题负责人, 2020.5.1~2023.5.1, 首都卫生发展科研专项

上消化道肿瘤早期标志物筛选及精准防控, 课题负责人, 2020.1.1~2022.12.31, 北京市卫健委

基于人工智能的胃癌发生相关分子特征系统挖掘及多维预测模型构建, 课题负责人, 2021.1.1~2022.12.30, 百度基金

Molecular Signatures Underlying the Progression of Intestinal Metaplasia: A Multi-omics Approach, 课题负责人, 2020.1.1~2021.12.31, Michigan Medicine-Peking University Health Science Center Joint Institute for Translational and Clin

Clinical and genetic epidemiology of atypical nevi, 课题负责人, 2016.7.1~2019.6.30, Dermatology Foundation Career Development Award

胃癌智慧医疗综合防诊治体系的建立及临床应用, 子课题负责人, 2019.1.1~2021.12.31, 北京市属医学科研院所公益发展改革项目

社会任职

  • 中国抗癌协会肿瘤筛查与早诊早治专业委员会常委兼秘书长
  • 中国抗癌协会理事
  • 中国抗癌协会肿瘤流行病学专业委员会常委
  • Springer Nature癌症与肿瘤期刊部中国顾问委员会委员
  • 中国科协第十届全国代表大会代表

学习、工作经历

  • 2014.4.3~2017.7.3,美国布朗大学助理教授、博士生导师
  • 2012.1.3~2014.3.3,美国NCI访问研究员
  • 2010.9.3~2012.1.3,哈佛大学医学院博士后
  • 2005.9.3~2010.7.3,北京大学临床肿瘤学院直博
  • 2000.9.3~2005.6.3,山东大学公共卫生学院本科